Browsing by Subject "Bioinformatics"
Now showing items 1-13 of 13
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The Acquisition of a Plastid by Haptophytes, Cryptophytes, and Photosynthetic Heterokonts
(East Carolina University, 2014)Red algae and green plants are known to have obtained their photosynthetic organelles, or plastids, through the endosymbiotic adoption of cyanobacteria. It is still widely debated as to how other eukaryotic alga such as ... -
AlienG2 - An Automated Analysis Tool for Genome-scale Prediction of Horizontal Gene Transfer
(East Carolina University, 2013)This thesis will present a method for predicting Horizontal Gene Transfer (HGT) events through the creation of a web-based application called AlienG2. HGT is the process of genetic exchange between distantly related ... -
Bioinformatic exploration of Hoxa2, Hoxb2, Hoxa11, and Hoxd11 in vertebrate evolution
(2015)The purpose of this bioinformatic project was to develop an understanding of how gene evolution shaped morphological complexity within the vertebrate lineage by evaluating protein sequence variations within hoxa2, hoxb2, ... -
Development of Computational Tools and Resources for Cotton microRNA Analysis
(East Carolina University, 2014)MicroRNAs (miRNAs) are an extensive class of small regulatory RNAs which regulate gene expression at the posttranscriptional levels. miRNAs target genes for mRNA cleavage or translation inhibition based on the complementary ... -
Effect of MicroRNA-34c on Regenerative Axon Growth in Dorsal Root Ganglion Neurons of the Peripheral Nervous System
(East Carolina University, 2011)The peripheral nervous system is unique in its ability to regenerate axons after injury. Our lab previously assessed the miRNA expression levels of the regenerating sciatic nerve which indicated miR-34c up-regulation. ... -
Genome-Wide Identification And Expression Analysis Of TCP Transcription Factors In Cotton
(East Carolina University, 2015)TCP proteins are plant-specific transcription factors known to perform a variety of physiological functions during plant growth and development. In the current study, we performed for the first time the comprehensive ... -
Intron position in RNA polymerase genes and their relationship to eukaryotic phylogenies
(East Carolina University, 2010)Over the past two decades, there has been an increasing amount of research devoted to the study of intron evolution and its relationship to eukaryotic phylogeny. Previous studies have shown that a large percentage of ... -
Lateral Gene Transfer between Bacteria and Trichoderma reesei
(East Carolina University, 2012)Lateral gene transfer (LGT) has played an important role in shaping the `tree of life'. It has promoted evolution by generating gene redundancies, which allow for more freedom in terms of allowed mutations in a genome, ... -
miRCancer : a microRNA-Cancer Association Database and Toolkit Based on Text Mining
(East Carolina University, 2010)MicroRNAs (miRNAs) are a class of single-stranded small non-coding RNAs. Study of miRNAs has been a fast growing field since the first miRNA was discovered in 1993. Many findings indicate that miRNA plays an important role ... -
Molecular evolution of venom proteins in Ctenidae (Order: Araneae) spiders
(East Carolina University, 2021-01-20)Spiders comprise the largest group of venomous animals and are a pivotal component of the global ecosystem with approximately 50,000 species spread across nearly every habitat on Earth. The family Ctenidae Keyserling, 1877 ... -
Neurological Effects Of A Single Low Level Blast Overpressure Exposure : Behavior And Micro RNA Mechanisms Of Mild Traumatic Brain Injury In A Rodent Model
(East Carolina University, 2015)The increased use of explosive devices within warfare and acts of terrorism has allowed blast overpressure exposure (BOE) to become a significant concern. The most common wound sustained by BOE is blast-induced mild traumatic ... -
Selective Recruitment of Germ Cell mRNAs by eIF4 Factors
(East Carolina University, 1/13/16)During germ line development critical steps in the proliferation and differentiation of stem cells into oocytes and sperm are regulated by mRNA translational control. This regulation changes the subset of proteins being ...