Browsing by Subject "HTLV-1"
Now showing items 1-6 of 6
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Direct Inhibition of RNAse T2 Expression by the HTLV-1 Viral Protein Tax
(2011-08)Adult T-cell leukemia (ATL) is one of the primary diseases caused by Human T-cell Leukemia Virus type 1 (HTLV-1) infection. The virally-encoded Tax protein is believed to initiate early events in the development of this ... -
HUMAN T-CELL LEUKEMIA VIRUS TYPE 1-ENCODED PROTEIN HBZ INCREASES VIRAL INFECTION
(East Carolina University, 2017-05-04)Human T-lymphotropic virus type 1 (HTLV-1) is a complex retrovirus, infecting CD4+ T lymphocytes. About 10 million people worldwide are infected with HTLV-1. HTLV-1 has been linked to adult T-cell leukemia (ATL), a disease ... -
INTERACTION BETWEEN HTLV-1 BASIC LEUCINE ZIPPER FACTOR (HBZ) AND HOST CELL PROTEINS PROMOTES CELLULAR TRANSFORMATION
(2016-04-26)Human T-cell Leukemia Virus Type 1 (HTLV-1) is a complex retrovirus which preferentially infects CD4+ T-cells. Endemic to Japan, regions of South America, Africa, and the Caribbean, HTLV-1 is transmitted through breastfeeding, ... -
NEUROPILIN-1 IS UPREGULATED BY HTLV-1 bZIP FACTOR AND INHIBITS CELL-TO-CELL TRANSMISSION OF HTLV-1
(East Carolina University, 2023-07-21)Human T-cell Leukemia Virus Type 1 (HTLV-1) is the etiologic agent of devastating diseases, including adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HTLV-1 ... -
The roles of the Ferlin Family in Human T-cell Leukemia Virus Type 1 Infection
(East Carolina University, 2023-12-04)Over 20 million people are infected with Human T-Cell Leukemia Virus type 1 (HTLV-1). HTLV-1 infection can cause diseases like aggressive Adult T-Cell leukemia and HTLV-1 associated myelopathy. These diseases are resistant ... -
Upregulation of Human T-Cell Leukemia Virus Type 1 Antisense Transcription by the Viral Tax Protein
(East Carolina University, 2009-02)Several studies have recently demonstrated the existence of human T-cell leukemia virus type 1 (HTLV-1) antisense transcripts, which allow the synthesis of the newly described HBZ protein. Although previous reports have ...