Browsing by Subject "Poxviruses"
Now showing items 1-3 of 3
-
Characterization of the Vaccinia Virus A35R Protein and Its Role in Virulence
(East Carolina University, 2006-01)The vaccinia virus A35R gene is highly conserved among poxviruses and encodes a previously uncharacterized hydrophobic acidic protein. Western blotting with anti-A35R peptide antibodies indicated that the protein is ... -
Effects of Modified Vaccinia Virus Ankara Expressing Mesothelin and the Poxvirus Immunoregulatory A35R gene in the Treatment of Murine Pancreatic Cancer
(East Carolina University, 2012)Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Pancreatic tumors over-express the protein mesothelin, and therefore, it is used as a tumor target antigen for vaccine development. ... -
VACCINIA VIRUS O1L VIRULENCE GENE AND PROTEIN LOCALIZATION
(2015)Smallpox killed an estimated 500 million people in the twentieth century alone. Although this fatal disease was eradicated from the world over thirty years ago, its potential use as a bioterrorism agent remains a concern. ...