Browsing by Subject "Colon (Anatomy)--Cancer"
Now showing items 1-5 of 5
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The Effects of Gastrin and Hox-A1 on HT-29 Cell Proliferation
(East Carolina University, 2013)Gastrin is a gastrointestinal peptide hormone synthesized in G cells and secreted in the antrum of the stomach. Though its primary role is to stimulate the secretion of gastric acid by parietal cells, it is also involved ... -
The effects of sodium butyrate on Hox gene expression in a human colorectal adenocarcinoma cell line, HT29.
(East Carolina University, 2013)Hox genes are a subgroup of the large family of homeobox containing genes, known to pattern anterior/posterior and proximal/distal axes during embryonic development. More recently Hox gene research has focused on the role ... -
Modeling survival in colon cancer: a methodological review
(East Carolina University, 2007-02-12)The Cox proportional hazards model is the most widely used model for survival analysis because of its simplicity. The fundamental assumption in this model is the proportionality of the hazard function. When this condition ... -
NOVEL NUCLEOLAR LOCALIZATION OF SYNAPTOPODIN-2 ISOFORM IN PROLIFERATING HT-29 CELLS
(East Carolina University, 2021-07-13)Members of the Synaptopodin family regulate [alpha]-actinin and actin-bundling activity, in an isoform specific manner (Asunama et al., 2005). The ability to affect actin polymerization and bundling highlights the critical ... -
SYNAPTOPODIN-2 ISOFORM A AND D EXPRESSION IN HT-29 HUMAN COLON ADENOCARCINOMA CELLS
(East Carolina University, 2013)Synaptopodin-2 is a largely unfolded actin-binding protein that also possesses the characteristics of a hub protein. Synaptopodin-2 has other known binding partners such as filamin and [alpha]-actinin (Weins, et al. 2001 ...