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Characterization of the Role of Mcm10 in DNA Replication in Drosophila melanogaster
(East Carolina University, 2013)
Replication of the genome and proper formation, and packaging, of chromatin are processes essential to eukaryotic life. Maintenance of epigenetic chromatin states is essential for faithfully reproducing the transcriptional ...
Responses of Leaf Litter Breakdown Rates and Microbial Enzyme Activity to Salinity in North Carolina Wetlands
(East Carolina University, 2014)
Sea-level rise and human activities are causing the increase of salinity in coastal freshwater wetlands. Increased salinity in some wetlands has been found to accelerate leaf litter decomposition, an important driver of ...
Inhibitory and oxidative effects of gossypol on MCF7 Breast Cancer cells in vitro
(East Carolina University, 2013)
Human cancer is the second leading cause of death in the United States and breast cancer is responsible for the second highest number of deaths in women with cancer worldwide. Today, cancer is becoming more and more ...
SPATIAL EXPRESSION OF MATRIX AND MATRIX RECEPTOR PROTEINS IN THE DEVELOPING SYNOVIAL JOINT
(East Carolina University, 2013)
Little is understood about the complex spatial and temporal molecular interactions necessary to form a fully functional synovial joint. Understanding molecular pathways and signaling within the developing joint continues ...
Fishing For The Evolutionary Bases Of Female Ornamentation
(East Carolina University, 2015)
Sexual dimorphism, or phenotypic differentiation of the sexes, is widespread amongst animals. It is understood mainly in the context of sexual selection, i.e. selection on mating success, with such selection typically ...
REPRODUCTIVE ISOLATION AND MIMETIC DIVERGENCE IN THE POISON FROG RANITOMEYA IMITATOR
(East Carolina University, 2014)
Understanding the process of speciation requires examination of various stages of its progress. This work focuses on the early stages of population divergence, where populations of a single species may show varying levels ...
The Effects of Crude Oil and Chemical Dispersant Exposure on Danio rerio (zebrafish) Embryonic Development
(East Carolina University, 2014)
Crude oil has been shown to cause defects in cardiovascular development in a variety of teleost species. We used the zebrafish, Danio rerio as a model to test the effects of oil and dispersant on cardiac development and ...
Spatial Ecology and Seasonal Habitat Use of the King Rail (Rallus elegans) along the Atlantic Coast
(East Carolina University, 2014)
TThe King Rail (Rallus elegans) continues to experience population declines throughout its range. Due to its secretive nature and occupancy of densely vegetated marshes, little is known about the behavior and ecology of ...
DETECTION AND DISTRIBUTION OF THE AMPHIBIAN FUNGAL DISEASE CHYTRIDIOMYCOSIS IN PERUVIAN AMPHIBIANS
(East Carolina University, 2012)
Chytridiomycosis is an amphibian disease caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd;Longcore et al. 1999). This disease has been identified by the Amphibian Conservation Action Plan as one of the main ...
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)
Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ...