Browsing Master's Theses by Author "Mannie, Mark D."
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DERIVATION OF TOLEROGENIC THERAPEUTIC VACCINES FOR MOUSE MODELS OF EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
Islam, S.M. Touhidul (East Carolina University, 2012)Multiple sclerosis (MS) is a chronic inflammatory disease that results in autoimmune demyelination of the human central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a widely-studied animal ... -
Mechanisms of resistance to the anti-CD4 monoclonal antibody W3/25 by encephalitogenic T cells
Marinakis, Christopher A. -
Structural and functional analysis of the Vaccinia virus O1 virulence protein
Weeks, Anastasia C. (East Carolina University, 2017-07-26)Poxviruses are double-stranded DNA viruses capable of causing disfiguring and deadly disease in a wide range of hosts, from insects to mammals. Orthopoxviruses (OPXV) encode many proteins that are not essential for viral ... -
The dual roles of interleukin-2 during T cell activation
Norris, Marcus S.