Browsing Master's Theses by Author "Zhang, Baohong"
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Effect of green tea Polyphenon 60 on microRNA expression in MCF-7 breast cancer cells
Fix, Lindsey Nicole (East Carolina University, 2010)In Western countries, breast cancer is the most common form of cancer and it is the second leading cause of female cancer death in America. The biochemical basis of the observed anti-oncogenic properties of green tea has ... -
Effects of 5-fluorouracil Drug Treatment on the Expression Profile of MicroRNAs in MCF7 Breast Cancer Cells
Shah, Maitri Yogen (East Carolina University, 2010)Breast cancer is one of the leading causes of deaths in women worldwide. 5-flourouracil (5-FU) is a classic chemotherapeutic drug that has been widely used in the treatment of breast cancer patients. In this study, using ... -
A Functional Analysis of microRNAs in Nicotiana tabacum
Burklew, Caitlin E. (East Carolina University, 2012)MicroRNAs (miRNAs) are a newly discovered class of endogenous post-transcriptional gene regulators that are typically 20-22 nucleotides in length that do not code for proteins. MiRNAs regulate gene expression by either ... -
Genome wide identification of ARF transcription factor gene family and their expression analysis in sweet potato
Pratt, Isaac (East Carolina University, 2021-07-15)Auxin response factors (ARFs) are a family of transcription factors that play an important role of auxin regulation through their binding with auxin response elements. ARF genes are represented by a large multigene family ... -
Genome-Wide Identification And Expression Analysis Of TCP Transcription Factors In Cotton
Ma, Jun (East Carolina University, 2015)TCP proteins are plant-specific transcription factors known to perform a variety of physiological functions during plant growth and development. In the current study, we performed for the first time the comprehensive ... -
Identification, Characterization, and Abiotic Stress Analysis of microRNAs in Nicotiana tabacum
Frazier, Taylor Price (East Carolina University, 2010)microRNAs (miRNAs) are non-coding RNAs with short sequences that negatively regulate gene expression at the post-transcriptional levels by either binding to mRNAs for degradation, or by inhibiting protein translation. ... -
Inhibitory and oxidative effects of gossypol on MCF7 Breast Cancer cells in vitro
Winfrey, William Brandon (East Carolina University, 2013)Human cancer is the second leading cause of death in the United States and breast cancer is responsible for the second highest number of deaths in women with cancer worldwide. Today, cancer is becoming more and more ... -
Reproductive Toxicity of Diazinon on Caenorhabditis elegans
Cobb, Juliana (East Carolina University, 2017-07-17)Worldwide, pesticide usage is on the rise. From 2006-2007, the global market saw a 1% increase in overall pesticide usage (Environmental Protection Agency 2012), a small percentage until you consider that one percent ... -
The Effects of Nicotine on Histone Modifications in Carnorhabditis Elegans
Parker, Daniel H. (2017-07-13)Early development stages have been known to be very susceptible to certain types of stress. Tobacco smoke is one of these major stresses that will affect them during this stage and can increase how likely they are to become ... -
Three Generations, One Future: A Systematic Analysis on Nicotine's Effect across generations in C. elegans.
Taki, Faten Ahmad (East Carolina University, 2013)Tobacco smoking is a worldwide epidemic that is responsible for diseases and death rates that surpass those attributed to a combination of other causes (e.g. cancer, HIV, accidents). A major mediator of tobacco-smoke related ... -
TITANIUM DIOXIDE NANOPARTICLES AFFECT THE GROWTH AND MIRNA EXPRESSION OF SWITCHGRASS (PANICUM VIRGATUM)
Boykov, Ilya N. (East Carolina University, 2017-06-28)Nanoparticle TiO2 is a common chemical used in paint, plastic, paper, ceramics, coated fabrics, floor coverings, printing ink, roofing granules, cosmetics, dyes and even food and drugs. As increasing usage of TiO2, it is ... -
Toxic Effects of Chlorpyrifos Exposure on Development of Caenorhabditits Elegans
Adams, Kevin (East Carolina University, 2016-12-15)Chlorpyrifos is a commonly utilized organophosphate pesticide, and as recently as 2007, was the most commonly used insecticide within the United States. Its ubiquity is concerning given its potential to cause developmental ...