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IS PREDATION BY TURTLES SUFFICIENTLY STRONG TO AFFECT BIODIVERSITY WITHIN FISHLESS PONDS?
(East Carolina University, 2011)
Ecologists have long known that predation can have a strong effect on the diversity and abundance of prey in ecological communities. Much evidence on the importance of predation in aquatic systems has stemmed from studies ...
Characterization of Two Novel Mutants of DNA Polymerase Delta in Drosophila melanogaster
(East Carolina University, 2011)
DNA is the genetic material for all living organisms which is constantly being unpackaged, replicated and repackaged. The replication of this genetic material involves numerous different proteins; however, DNA polymerase ...
Photofrin-Mediated Electroporation-Assisted Photodynamic Therapy of MCF-7 Human Breast Cancer and B16-F10 Mouse Melanoma Cells
(East Carolina University, 2011)
Photodynamic therapy is a relatively new player on the field of cancer treatment that involves the injection of a nontoxic light-sensitive drug followed by light excitation, creating reactive oxygen species that cause ...
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)
Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ...
DISINTEGRIN-LIKE DOMAIN IN KSHV ENCODED gB IS A NECESSITY TO PROMOTE VIRUS LATENCY
(East Carolina University, 2011)
KSHV glycoprotein B (gB) is a lytic structural protein expressed on the envelope of mature virions and on the membrane of cells supporting lytic infection. Previous studies have identified that in addition to the role of ...
Hypoxia and Serum Deprivation in Human Mesenchymal Stem Cells, and the Protective Role of Thymosin [Beta]-4
(East Carolina University, 2011)
Background: Current literature suggests nutrient deprivation and hypoxia affect human mesenchymal stem cell (hMSC) survival after cell transplantation. Wound-healing protein Thymosin [beta]-4 (T[beta]-4) has been shown ...