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Skipping the Injuries: A Biomechanical and Metabolic Comparison Between Skipping & Running
(East Carolina University, 2016-05-20)
Introduction: Benefits of aerobic exercise are apparent; the rising awareness has caused an increase in running participation and, an undeniable trend toward injury. The inherit injury risk associated with running calls ...
Effects of High-Insulin Exposure on Mitochondrial Content in Skeletal Muscle Myotubes from Lean & Severely Obese Individuals: A Time Course Analysis
(East Carolina University, 2016-08-01)
Skeletal muscle is the site at which highly regulated energetic processes take place as a means of maintaining both tissue-specific and whole-body metabolism. With the development of severe obesity (BMI [greater-than] or ...
Substrate Utilization During Submaximal Exercise in Children with a Severely Obese Mother and Response to Exercise Training
(East Carolina University, 2016-08-18)
The aim of this study was to compare fat metabolism during submaximal exercise in children with a severely obese mother (BMI[greater than or equal to]35 kg/m2) to children with a lean, non-obese mother (BMI[less than or ...
Unravelling the mechanisms of menopause-induced insulin resistance: novel roles for estradiol in skeletal muscle mitochondrial function
(East Carolina University, 2016-11-16)
Menopause results in a progressive decline in ovarian production of 17[beta]-estradiol (E2), increased adiposity and a higher risk for type-2 diabetes, but hormone replacement therapies containing E2 reverse most of these ...
Peroxisomal-Mitochondrial Metabolic Interactions in Lipid Metabolism in Human Skeletal Muscle
(East Carolina University, 2016-11-16)
Peroxisomal activity and associated functions, including [beta]-oxidation contributions toward maintaining cellular lipid homeostasis, is poorly defined in extra hepatic tissues, most especially in human skeletal muscle ...
Identifying Primary Healthcare Providers’ Barriers to Prescribing Physical Activity as Medicine in Comparison to their own Physical Activity Level
(East Carolina University, 2016-06-01)
Abstract Objective. To examine healthcare providers' barriers to counseling physical activity to their patients. Then examine the same primary providers' own physical activity level over the course of 7 days (1 week) using ...
ELUCIDATION ON THE MECHANISM OF CAMKKα AS A PRO-GROWTH KINASE IN MOUSE SKELETAL MUSCLE
(East Carolina University, 2016-12-15)
Type 2 diabetes affects ~25 million people in the U.S., and is the primary cause of non-traumatic lower limb amputation and the leading cause of blindness in adults. Major risk factors for the development of type 2 diabetes ...
The Relationship Between the Hamstrings to Quadriceps Strength Ratio and Anterior Cruciate Ligament Forces
(East Carolina University, 2016-07-11)
Injury to the anterior cruciate ligament (ACL) is one of the most common knee injuries in sports and is associated with other serious health concerns like osteoarthritis (OA). Forces developed by the hamstrings and quadriceps ...
Effect of previous hamstring strain on Anterior Cruciate Ligament (ACL) forces
(East Carolina University, 2016-08-18)
Introduction: Anterior Cruciate Ligament (ACL) injuries are very common in the athletic population. While the hamstring muscles help protect the ACL, hamstring strain injuries (HSI) are also common in sports. After HSI, ...