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Measured Resting Energy Expenditure Using a Fixed Function Indirect Calorimeter in the Clinical Setting as a Predictor of Success with Weight Change in an Obese Pediatric Population
(East Carolina University, 2010)
The American Dietetic Association (ADA) standard of care for obese adults utilizes indirect calorimetry for calculating caloric targets for weight loss (1). Even though rates appear to be leveling off (2), childhood obesity ...
Skeletal Muscle Eukaryotic Elongation Factor 2 (eEF2) Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP-Activated Protein Kinase (AMPK) Activity
(East Carolina University, 2010)
Sarcopenia is associated with an age-related decrease in skeletal muscle mass, which can result in decreases in strength and physical functioning in the older population. Resistance training interventions are not completely ...
The Influence of Energy Expenditure on Mitochondrial Functions, Oxidative Stress and Insulin Resistance under Metabolic Oversupply Conditions
(East Carolina University, 2011)
Mitochondrial respiratory capacity and oxidative stress have been implicated in the development of insulin resistance (IR) and type II diabetes. A causative role of mitochondrial oxidative stress in the etiology of ...
REGULATION OF LIPOLYSIS BY [BETA]-ADRENERGIC ACTIVATION AND EXERCISE IN OBESE AFRICAN-AMERICAN AND CAUCASIAN WOMEN
(East Carolina University, 2012)
African-American women (AAW) are twice as likely to be obese as Caucasian women (CW); however, previous in-vitro studies have shown that AAW have higher densities of beta-adrenergic receptors (B-AR) in the subcutaneous ...
The Effects of Aerobic Exercise Training in Children with Lean and Extremely Obese Biological Mothers
(East Carolina University, 2011)
The purpose of this study was to compare fat oxidation rates between children of lean biological mothers (CLP) (BMI[less than or equal to]28kg/m[superscript]2) and children of extremely obese biological mothers (COP) ...
Obese Children Have a Lower Lipolytic Response to an Acute Bout of Exercise When Compared to Lean
(East Carolina University, 2010)
Over 17% of American children are obese. These are epidemic proportions considering the associated risk of heart disease and Type 2 diabetes. Excess fat is caused from an imbalance in energy stored versus energy expended. ...
INTERVENTION TO REDUCE SEDENTARY TIME AND IMPROVE CARDIOMETABOLIC RISK FACTORS AMONG SEDENTARY EMPLOYEES
(East Carolina University, 2012)
Background: More than half of the US adult population is sedentary and this type of behavior is known to increase an individual's risk for overweight/obesity, hypertension, cardiovascular disease, stroke, type 2 diabetes ...
The Effect of Eccentric Hamstring Strength Training on Muscle Function
(East Carolina University, 2015)
The high prevalence of hamstring strain injury in sports, coupled with detrimental performance and financial effects of hamstring injuries, stress the necessity to implement an intervention capable of minimizing hamstring ...
Evaluating Two Measures of Postural Stability in Response to Perturbations in People with Diabetic Neuropathy
(East Carolina University, 2015)
Diabetic neuropathy is a common complication of diabetes. It is characterized by a marked decrease in proprioception, particularly in the lower body. This reduced proprioception leads to an increase in falls risk in this ...
THE EFFECTS OF CIRCADIAN RHYTHM ON INFLAMMATORY RESPONSE AND CYTOKINE LEVELS IN HEPATIC MACROPHAGES
(East Carolina University, 2014)
In mammals, many aspects of daily behavior and physiology such as the sleep-wake cycle, body temperature, and liver metabolism are regulated by endogenous circadian mechanisms. Despite tissue-specific physiological ...