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The Influence of the War of 1812 on Great Lakes Shipbuilding
(East Carolina University, 2012)
The purpose of this thesis is to determine whether the War of 1812 influenced ship construction techniques on the Great Lakes. During the War of 1812, much of the fighting in the North American theater of war primarily ...
Defining Eastern North Carolina Upriver Steamboats Through Tar River Archaeology and History
(East Carolina University, 2012)
This thesis will identify the salient features of North Carolina upriver steamboats and their relationships to steamboats from a variety of regions in the United States in an effort to understand the means by which people ...
Consequences of Reduced Versican Expression in Embryonic Chick Synovial Joint Development
(East Carolina University, 2012)
The different mechanisms involved in vertebrate synovial joint development are actively being uncovered. A variety of studies have thus far discovered the involvement of several large molecules in the processes of joint ...
ESTABLISHING LINKAGE BETWEEN GINS COMPLEX SUB-UNIT Sld5 AND CHECKPOINT PROTEIN Chk2 (loki) USING DROSOPHILA MELANOGASTER AS MODEL ORGANISM
(East Carolina University, 2012)
Eukaryotic DNA replication is controlled by a number of proteins that ensures the process takes place accurately. GINS, a hetero-tetrameric protein complex is known to be essential for the initiation and progression of ...
Cardiac and Mitochondrial Adaptations in Response to Aging and Doxorubicin in Rats Bred for Divergent Aerobic Capacities
(East Carolina University, 2012)
Doxorubicin (DOX) remains as one of the most widely prescribed and effective anticancer agents. A major limitation of the therapeutic effectiveness of the drug is the occurrence of irreversible, progressive, dose-dependent ...
Effects of Modified Vaccinia Virus Ankara Expressing Mesothelin and the Poxvirus Immunoregulatory A35R gene in the Treatment of Murine Pancreatic Cancer
(East Carolina University, 2012)
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Pancreatic tumors over-express the protein mesothelin, and therefore, it is used as a tumor target antigen for vaccine development. ...
The Final Ambush : An Adapted Battlefield Analysis of the U-576 Attack Upon Allied Convoy KS-520 off Cape Hatteras During the Second World War
(East Carolina University, 2012)
The Battle of the Atlantic was the longest, largest, and most complex military action of the Second World War. The battle involved Allied, Axis, and neutral nations, resulting in both military and civilian casualties. At ...
"From Quiet Woods to Tide Kissed Shore" : Searching for the Colonial Port of Sunbury, Georgia
(East Carolina University, 2012)
This thesis chronicles efforts to examine a unique colonial waterfront complex in Sunbury, Georgia comprised of four distinct colonial wharf sites. To carry out an explanation of these features and Sunbury's overall ...
The foraminiferal signature of recent Gulf of Mexico hurricanes
(East Carolina University, 2012)
Down-core activities of ⁷Be, ²³⁴Th, and ²¹⁰Pb, as well as X-radiography, have indicated the existence of sediments deposited by hurricanes Ivan (2004), Katrina (2005), and Rita (2005) on the continental margin west of the ...
Perceptions of HIV Risk Among African American Women in Eastern North Carolina
(East Carolina University, 2012)
This project involved the collection and analysis of data from pre-and post-tests and five focus groups with 54 community-dwelling, middle-aged African American women in Eastern North Carolina, in order to explore the ...