Browsing Biology by Title
Now showing items 162-181 of 460
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Effect of Versican G1 Domain Overexpression on Hyaluronan, Hyaluronidase-2, and Synovial Joint Formation in the Embryonic Chick
(East Carolina University, 2013)Versican, an extracellular chondroitin sulfate proteoglycan which binds hyaluronan, has been hypothesized to play a role in synovial joint formation in the chick embryo. Several studies have shown versican to be involved ... -
Effects of 5-fluorouracil Drug Treatment on the Expression Profile of MicroRNAs in MCF7 Breast Cancer Cells
(East Carolina University, 2010)Breast cancer is one of the leading causes of deaths in women worldwide. 5-flourouracil (5-FU) is a classic chemotherapeutic drug that has been widely used in the treatment of breast cancer patients. In this study, using ... -
EFFECTS OF A REVERSE OSMOSIS-WATER TREATMENT PLANT BRINY CONCENTRATE DISCHARGED INTO AN ESTUARY.
(East Carolina University, 2010)Reverse Osmosis Water Treatment Plants (RO-WTPs) create potable water and a briny concentrate that must be disposed; often it is discharged into nearby surface waters. Currently, there is no published research to examine ... -
Effects of Aluminum Oxide Nanoparticles on the Growth, Development, and microRNA Expression of Tobacco ()
(2012)Nanoparticles are a class of newly emerging environmental pollutions. To date, few experiments have been conducted to investigate the effect nanoparticles may have on plant growth and development. It is important to study ... -
The Effects of Crude Oil and Chemical Dispersant Exposure on Danio rerio (zebrafish) Embryonic Development
(East Carolina University, 2014)Crude oil has been shown to cause defects in cardiovascular development in a variety of teleost species. We used the zebrafish, Danio rerio as a model to test the effects of oil and dispersant on cardiac development and ... -
The effects of elevated temperature and dissolved ρCO2 on a marine foundation species
(2017-04)Understanding how climate change and other environmental stressors will affect species is a fundamental concern of modern ecology. Indeed, numerous studies have documented how climate stressors affect species distributions ... -
The effects of environmental nickel toxicity upon survival, growth, reproduction, fecundity, and lifespan of nematodes Caenorhabditis elegans, Pristionchus pacificus, and Caenorhabditis briggsae
(East Carolina University, 2012)Nickel (II) is a common component of many natural products and man-made devices. Due to its frequent use in everyday life, relatively large amounts of nickel are being released into the environment. Nickel, however, is a ... -
The Effects of Gastrin and Hox-A1 on HT-29 Cell Proliferation
(East Carolina University, 2013)Gastrin is a gastrointestinal peptide hormone synthesized in G cells and secreted in the antrum of the stomach. Though its primary role is to stimulate the secretion of gastric acid by parietal cells, it is also involved ... -
Effects of Land Use Change on Juvenile Fishes, Blue Crab, and Brown Shrimp Abundance in the Estuarine Nursery Habitats of North Carolina
(East Carolina University, 2011)The U.S. coastal region is home to more than half of the American population. Also, the coastal counties' population is growing much faster than that of inland counties. With a high density and an increasing population, ... -
Effects of Modified Vaccinia Virus Ankara Expressing Mesothelin and the Poxvirus Immunoregulatory A35R gene in the Treatment of Murine Pancreatic Cancer
(East Carolina University, 2012)Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Pancreatic tumors over-express the protein mesothelin, and therefore, it is used as a tumor target antigen for vaccine development. ... -
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ... -
Effects of nutrient addition on plant community composition: a functional trait analysis in a long-term experiment
(East Carolina University, 2018-07-19)The effects of nutrient availability on plant community composition and diversity have been well-documented, but the mechanisms behind the community response remain unclear. Plant species interact with variation in the ... -
Effects Of Nutrient Availability And Disturbance On The Composition And Diversity Of Soil Microorganisms
(East Carolina University, 2015)Determining how factors such as disturbance and nutrient availability affect species diversity in a community has been a major goal of community ecology. The purpose of this study was to look at how species diversity and ... -
THE EFFECTS OF PRENATAL LEAD EXPOSURE ON THE DEVELOPMENT OF BIOMARKERS OF ALZHEIMER’S DISEASE
(2015-04)While often well known for its adverse effects on memory, Alzheimer’s disease (AD) is also noteworthy for being the sixth leading cause of death in the United States. An estimated 5.2 million Americans had the disease as ... -
The effects of sodium butyrate on Hox gene expression in a human colorectal adenocarcinoma cell line, HT29.
(East Carolina University, 2013)Hox genes are a subgroup of the large family of homeobox containing genes, known to pattern anterior/posterior and proximal/distal axes during embryonic development. More recently Hox gene research has focused on the role ... -
Effects of temperature, flow, and climate factors on inter-annual variation of larval fish assemblages in a coastal watershed
(East Carolina University, 2017-12-13)Predicting how populations will respond to future climate scenarios is of interest to ecologists and resource managers. Recent interest in the effect large-scale climate patterns have on local environmental conditions has ... -
Effects of Zinc Oxide Nanoparticles on the Pharyngeal Pumping and Neurological Behavior of C. elegans
(East Carolina University, 2018-08-02)Cogent data regarding the effects of manufactured zinc oxide nanoparticles (ZnO-NPs) on human health and other organisms is limited. With the prominence of manufactured ZnO - NPs increasing rapidly in recent years, the ... -
EGID: an ensemble algorithm for improved genomic island detection in genomic sequences
(2011)Genomic islands (GIs) are genomic regions that are originally transferred from other organisms. The detection of genomic islands in genomes can lead to many applications in industrial, medical and environmental contexts. ... -
Elucidating Gene Function with the use of Genome Wide Association Study (GWAS)
(East Carolina University, 2015)DNA replication and cell proliferation are intensely studied subjects. There have been countless experiments and hours put into better understanding how DNA is replicated and compacted, and how cells are able to proliferate ... -
Elucidating the mechanisms of Nickel as an animal mutagen
(East Carolina University, 2016-04-28)Nickel is an essential metal for many organisms. Nickel occurs naturally from volcanism and weathering of stone. Recently production of nickel from anthropogenic sources has overtaken natural production. Combustion of ...