Browsing Biology by Title
Now showing items 235-254 of 513
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Gamma Protocadherin Expression in the Embryonic Chick Nervous System
(East Carolina University, 2007)Protocadherin gamma (pcdh-gamma) family expression was examined in the embryonic chick central nervous system by in situ hybridization. Transcripts were visualized in discrete regions of fore-, mid-, and hindbrain at stages ... -
Gene Expression and the Evolution of Reduced Sexual Dimorphism in a Threespine Stickleback Color Trait
(East Carolina University, 2017-01-03)Elucidating the processes and mechanisms responsible for sexual dimorphism has been a central task for evolutionary biologists since Darwin first proposed the concept of sexual selection. However, our understanding of the ... -
Gene Expression Divergence Between Zebra Finch (Taeniopygia Guttata) Subspecies And Gene Regulation In Hybrids
(East Carolina University, 2015)Since the publication of Mayr's Systematics and the Origin of Species, birds have been important model organisms for studies regarding evolutionary processes such as sexual selection and speciation. In this study, I will ... -
Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback
(2015-12)Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ... -
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
(2016-01)Reduced glomerular filtration rate defines chronic kidney disease and is associated with cardiovascular and all-cause mortality. We conducted a meta-analysis of genome-wide association studies for estimated glomerular ... -
Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial
(2014-08)Background: B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke. We performed a genome-wide association study ... -
The Genetic Basis of Pigmentation Variation in Domesticated Zebra Finches
(2014)The zebra finch is the most common estrildid finch native to Australia and Southeast Asia. The zebra finch has also been domesticated and is now a common pet and experimental model system for research. As part of the ... -
Genetic mapping of the female mimic morph locus in the ruff
(2013)Background Ruffs (Aves: Philomachus pugnax) possess a genetic polymorphism for male mating behaviour resulting in three permanent alternative male reproductive morphs: (i) territorial ‘Independents’, (ii) non-territorial ... -
A Genetic Mosaic Screen Reveals Ecdysone-Responsive Genes Regulating Drosophila Oogenesis
(2016-08)Multiple aspects of Drosophila oogenesis, including germline stem cell activity, germ cell differentiation, and follicle survival, are regulated by the steroid hormone ecdysone. While the transcriptional targets of ecdysone ... -
A Genetic Screen for Mcm10: Interactions Between Mcm10 and Deficiency Regions on the Third Chromosome of Drosophila Melanogaster
(2015)Mis-regulation of the Mcm10 gene has been linked with multiple forms of cancer, including many forms of breast cancer (Thu, Y. 2014). Despite this, the role of Mcm10 in cancer is not yet fully known. One way to study a ... -
Genetic variation corroborates subspecific delimitation in the Namib fog-basking beetle, (Haag) (Tenebrionidae, Coleoptera)
(2013)The fog-basking beetle, Onymacris unguicularis (Haag, 1875), is currently listed as a polytypic form comprising two subspecies. A flightless substrate specialist, the beetleis endemic to vegetationless dunes in the Namib, ... -
Genome Analysis of Planctomycetes Inhabiting Blades of the Red Alga
(2016-03)Porphyra is a macrophytic red alga of the Bangiales that is important ecologically and economically. We describe the genomes of three bacteria in the phylum Planctomycetes (designated P1, P2 and P3) that were isolated from ... -
Genome sequencing and analysis of the paclitaxel-producing endophytic fungus NRRL 62431
(2014)Background Paclitaxel (Taxol™) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted to the Taxus species until it was discovered in Taxomyces andreanae, ... -
Genome-wide and molecular evolution analysis of the subtilase gene family in
(2014-12)Background Vitis vinifera (grape) is one of the most economically significant fruit crops in the world. The availability of the recently released grape genome sequence offers an opportunity to identify and analyze some ... -
Genome-Wide Functional Analysis of the Cotton Transcriptome by Creating an Integrated EST Database
(2011)A total of 28,432 unique contigs (25,371 in consensus contigs and 3,061 as singletons) were assembled from all 268,786 cotton ESTs currently available. Several in silico approaches [comparative genomics, Blast, Gene Ontology ... -
Genome-Wide Identification And Expression Analysis Of TCP Transcription Factors In Cotton
(East Carolina University, 2015)TCP proteins are plant-specific transcription factors known to perform a variety of physiological functions during plant growth and development. In the current study, we performed for the first time the comprehensive ... -
Genome-Wide Identification of R2R3-MYB Genes and Expression Analyses During Abiotic Stress in
(2016-03)The R2R3-MYB is one of the largest families of transcription factors, which have been implicated in multiple biological processes. There is great diversity in the number of R2R3-MYB genes in different plants. However, there ... -
Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of with Ischemic Stroke
(2014-03)Circulating homocysteine levels (tHcy), a product of the folate one carbon metabolism pathway (FOCM) through the demethylation of methionine, are heritable and are associated with an increased risk of common diseases such ... -
The genomes of two key bumblebee species with primitive eusocial organization
(2015-04-24)Background The shift from solitary to social behavior is one of the major evolutionary transitions. Primitively eusocial bumblebees are uniquely placed to illuminate the evolution of highly eusocial insect societies. ... -
Genomic Database Conundrum: Widespread Misannotation of rRNA Sequences as Protein Sequences
(East Carolina University, 2017-12-11)The genomics revolution introduced affordable technology capable of rapidly analyzing and comparing massive amounts of biological sequence data. Using the Basic Local Alignment Search Tool (BLAST) program on the National ...