Search
Now showing items 1-10 of 60
Epigenetic Effect of Modified Diet and Exercise on Drosophila Metabolic Phenotype and Cardiovascular Health
(2015-04)
Obesity is a growing world-wide epidemic. Overweight populations are prone to a variety of morbid conditions including diabetes type 2, cardiovascular diseases, and cancers. The catastrophic increase in obesity rates, which ...
THE EFFECT OF CHANGES IN SODIUM CONCENTRATIONS ON MITOCHONDRIA
(2015-05-01)
Atherosclerosis, hardening of the arteries, is the major cause of stroke, peripheral artery disease and heart attack. . Overproduction of superoxide anions in mitochondria can give rise to atherosclerosis. Superoxide anions ...
Hydrogeomorphology and Horizontal Movement of Juncus roemerianus
(East Carolina University, 2015)
Juncus roemerianus, black needlerush, is common in high marshes and occasionally in low marshes along the Mid-Atlantic and southern USA. Previous work found that J. roemerianus patches remained relatively stable in the ...
Elucidating Gene Function with the use of Genome Wide Association Study (GWAS)
(East Carolina University, 2015)
DNA replication and cell proliferation are intensely studied subjects. There have been countless experiments and hours put into better understanding how DNA is replicated and compacted, and how cells are able to proliferate ...
Targeting aberrant signaling in the EGFR1/HER2/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway : Novel therapeutic interventions in breast cancer
(East Carolina University, 2015)
Breast cancer is attributed to being the second most deadly cancer in American women. Approximately 1 in 8 women will be diagnosed with breast cancer during her lifetime, and prognosis is dependent upon the genetic make-up ...
Analysis of scn5Laa and scn5Lab Gene Function in Danio rerio (Zebrafish) Heart Development through TALENs/CRISPR-CAS9-mediated Gene Knockout
(East Carolina University, 2015)
Research in our laboratory is focused on understanding the molecular developmental genetic effects of crude oil exposure on vertebrate embryogenesis. Our research has demonstrated that exposure of zebrafish embryos to ...
INSIGHTS INTO THE HABITAT AND BREEDING BIOLOGY OF THE FEDERALLY ENDANGERED HERBACEOUS PLANT, THALICTRUM COOLEYI, AHLES
(East Carolina University, 2015)
Thalictrum cooleyi Ahles (Cooley's meadowrue, Ranunculaceae) is a dioecious species, endemic to fire-dependent, wet pine savannas of the southeastern US. T. cooleyi was listed as federally endangered in 1989; knowledge ...
Developmental Patterns of Cleistogamy and Chasmogamy in Triodanis perfoliata
(2015-05)
Some plants exhibit mixed mating, in which individual plants utilize both cross and self-fertilization. Dimorphic cleistogamy is one form of mixed mating. In plants that display dimorphic cleistogamy, both chasmogamous ...
Stress, Burnout, and Coping Mechanisms in Health Professionals Working in Pediatric Oncology
(2015)
Burnout syndrome is a destructive repercussion of experiencing various chronic stressors and is prevalent among health care professionals. It changes driven, ambitious, hardworking people into depressed, apathetic, error-prone ...
ASSESSMENT OF NICHE PARTITIONING IN CO-OCCURRING SILVERSIDES FROM THE ALBEMARLE AND PAMLICO SOUNDS OF NORTH CAROLINA
(2015-05-01)
The niche partitioning hypothesis predicts that two species cannot compete for the same limited resources and that one species should differentiate (genetically, morphologically or behaviorally), so that the two species ...