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SMAD3 OVEREXPRESSION ENHANCES VASCULAR SMOOTH MUSCLE CELL ATTACHMENT
(East Carolina University, 2016-04-28)
Cardiovascular disease (CVD) is the leading cause of death and illness in the United States and worldwide. Smooth muscle cell (SMC) migration and secretion of extracellular matrix materials are key components of adverse ...
EMBRYO DEVELOPMENT, SEED BANK POTENTIAL AND GERMINATION OF THE FEDERALLY ENDANGERED HERB OF PINE SAVANNAS, THALICTRUM
(East Carolina University, 2016-06-03)
Plant conservation efforts strongly rely on knowledge of species seed biology and viability for further propagation. Virtually nothing is known about the seed biology of the federally endangered Thalictrum cooleyi Ahles ...
ZOOPLANKTON COMMUNITY STRUCTURE AND ECOSYSTEM FUNCTION ACROSS A SALINITY GRADIENT
(East Carolina University, 2016-05-05)
Pre and post-colonization factors differentially affect community structure. Sea level rise is mixing formerly isoloted freshwater communities with salt water communities. These ponds have a large range of salinity, which ...
A validated protocol to quantify severity of male urogenital feminization using the MOUSE (Mouse objective urethral severity evaluation)
(2016-06-13)
Background
Congenital abnormalities vary in presentation, yet studies using model organisms tend to focus on occurrence rather than severity of the defect. Scoring severity of abnormalities in model systems allows explicit ...
Early Nicotine Exposure Altered Larval Neuromuscular Function and Adult Germline Apoptosis via MiRNA-Dependent Mechanisms
(East Carolina University, 2016-04-29)
MicroRNAs fine tune the expression of target genes needed for homeostasis. Our pilot study showed that nicotine altered 17% miRNAs in C. elegans larvae. Here, we investigated the role of microRNAs in mediating nicotine-induced ...
Climate Change Alters Trophic Interactions in Coastal Ecosystems
(East Carolina University, 2016-05-04)
Understanding the effects of multiple anthropogenic changes on local ecosystems is important for understanding community interactions. Because they lie at the interface between the land and sea coastal ecosystems are often ...