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TOXICITY OF METAL OXIDE NANOPARTICLES TO CAENORHABDITIS ELEGANS
(East Carolina University, 2012)
The increase in manufacturing and use of nanoparticles is expected to elevate levels of exposure to humans and other organisms. Presently, there is little understanding of the potential toxic effects of nanoparticle exposure. ...
Assessing cellular and genomic damage from environmental nickel using a GFP containing strain of Caenorhabditis elegans
(East Carolina University, 2013)
Nickel is a naturally found mineral that has become widely used for many electronic devices. As use and subsequent discarding of nickel containing products continues exposure to nickel increases. Nickel can cause external ...
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)
Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ...
Nickel as a mutagen and as an enabler of EMS genotoxicity in Caenorhabditis elegans
(East Carolina University, 2016-01-15)
Nickel is found naturally and vital for survival of some organisms. Nickel occurs as a metal as insoluble compounds and soluble compounds. Nickel exposure has increased due to urbanization from various sources including ...
Three Generations, One Future: A Systematic Analysis on Nicotine's Effect across generations in C. elegans.
(East Carolina University, 2013)
Tobacco smoking is a worldwide epidemic that is responsible for diseases and death rates that surpass those attributed to a combination of other causes (e.g. cancer, HIV, accidents). A major mediator of tobacco-smoke related ...
Nicotine Controlof Germline Cell Fate in Caenorhabditis elegans
(2015-05)
Nicotine dependence is the single largest cause of preventable death in the world, claiming 480,000 lives each year in the US alone, including those caused by secondhand smoke. In this study, we investigated the biological ...
Sub-lethal toxic effect of Bisphenol A on Caenorhabditis elegans : the role of stress resistance genes in BPA-induced growth inhibition
(East Carolina University, 2014)
Endocrine disrupting chemicals (EDCs) have become of concern for a variety of health issues. Bisphenol-A (BPA) is a widely studied EDC and has been characterized by its estrogen-like effects. BPA is a prevalent component ...
The Evolution of Organ Shape : Distal Tip Cell Migration and Gonadogenesis in Nematodes
(East Carolina University, 2013)
Animals display a variety of shapes in nature. The different shape of homologous organs allows them to adopt different functions and therefore, allows animals to live in different ecological niches. However, little is ...
Comparison of ZnO nanoparticles and ZnCl₂ induced germ cell apoptosis in Caenorhabditis elegans
(East Carolina University, 2014)
There is inadequate research data available on manufactured ZnO nanoparticles. Manufactured nanoparticles are widely used in various products and production of manufactured nanoparticles is becoming increasingly abundant. ...
Reproductive Toxicity of Diazinon on Caenorhabditis elegans
(East Carolina University, 2017-07-17)
Worldwide, pesticide usage is on the rise. From 2006-2007, the global market saw a 1% increase in overall pesticide usage (Environmental Protection Agency 2012), a small percentage until you consider that one percent ...