Browsing Health Sciences Campus by Title
Now showing items 374-393 of 564
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p53 and NGAL: dual regulatory roles in advanced prostate cancer
(East Carolina University, 2011)The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ... -
Pain Management after Cardiac Surgery
(East Carolina University, 2009)Postoperative pain relief is one of the most important concerns for patients undergoing cardiac surgery and is one of the most clinically challenging problems for nurses. It is widely recognized that postoperative pain can ... -
Participation in Community-Originated Interventions is Associated with Positive Changes in Weight Status and Health Behaviors in Youth
(2012-04-13)Purpose. To assess changes in children’s health behaviors and weight status after participation in community-originated interventions. ... -
A pathomechanical paradigm for treating the injured runner
(http://legeforeningen.no/spesial/Norsk-forening-for-idrettsmedisin-og-fysisk-aktivitet/Norsk-idrettsmedisin/?so=0, 2013)Pathological mechanics are thought to play a role in many common running injuries. A review of the biomechanical literature reveals that a given running injury may be associated with multiple faulty running mechanics. ... -
Patterns of Distress in African American Mothers of Preterm Infants
(East Carolina University, 2009-06)Objective: To examine inter-relationships among stress due to infant appearance and behavior in the NICU, parental role alteration stress in the NICU, depressive symptoms, state anxiety, posttraumatic stress symptoms, and ... -
Paul De Kruif: The Microbe Hunter and Author
(2009-08-31)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
Pediatric Palliative Care: A Quality Improvement Recommendation
(2015-06)In the United States, there are greater than 500,000 infants and children living with a life-threatening or life-limiting condition. Advances in healthcare allow children with life threatening or life limiting conditions ... -
The perceived impact of falling and the fear of falling on older adults living independently at a continuing care retirement community in eastern north carolina
(East Carolina University, 2010)This study was completed using the phenomenological research strategy to understand the effect that falling and the fear of falling has on independently living residents at a continuing care retirement community in eastern ... -
Perceptions of nursing as a career option held by men with experiences in military health care.
(East Carolina University, 2011)Despite notable efforts to present nursing as a viable career for men, the profession remains predominately female, and the modest changes in the numbers of men has not kept pace with the increasing demand for nursing ... -
Perceptions of the Community Food Environment and Related Influences on Food Choice Among Midlife Women Residing in Rural and Urban Areas: A Qualitative Analysis
(East Carolina University, 2009)Introduction—Qualitative research on food choice has rarely focused on individuals’ perceptions of the community food environment. Women remain gatekeepers of the family diet and food purchasing. Therefore we assessed ... -
Perfluorooctanoic acid-induced developmental cardiotoxicity in an avian model
(East Carolina University, 2013)Perfluorooctanoic acid (PFOA) is a synthetic chemical used in polyfluormer production. It is a widespread environmental contaminant and is known to induce developmental toxicity in rodent models. As several related compounds ... -
Perforated gastric corpus in a strangulated paraesophageal hernia: a case report
(East Carolina University, 2009-05-07)Introduction: Patients with paraesophageal hernias often present secondary to chronic symptomatology. Infrequently, acute intestinal ischemia and perforation can occur as a consequence of paraesophageal hernias with ... -
Peroxisome Proliferator-Activated Receptor-γ Regulates the Expression of Alveolar Macrophage Macrophage Colony- Stimulating Factor
(East Carolina University, 2008-07-01)Macrophage CSF (M-CSF) regulates monocyte differentiation, activation, and foam cell formation. We have observed that it is elevated in human pulmonary alveolar proteinosis (PAP) and in the GMCSF knockout mouse, a murine ... -
A Perspective on Systemic Nutrition and Nutritional Genomics
(East Carolina University, 2009)The brain and the gut work synergistically with each other and other organs. Reviewing nutrition systemically (rather than by single organs) is a holistic way for dietitians to evaluate their clients’ health status. ... -
Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death.
(East Carolina University, 1995-10)Protein kinase C (PKC) modulates growth, differentiation, and apoptosis in a cell-specific fashion. Overexpression of PKC-a in MCF-7 breast cancer cells (MCF-7-PKC-a cell) leads to expression of a more transformed phenotype. ... -
Physical Activity Levels of Patients Undergoing Bariatric Surgery in the Longitudinal Assessment of Bariatric Surgery (LABS) Study
(East Carolina University, 2008)Background- Bariatric surgery candidates' physical activity (PA) level may contribute to the variability of weight loss and body composition changes following bariatric surgery. However, there is little research describing ... -
Physical and Functional Interactions between the Herpes Simplex Virus UL15 and UL28 DNA Cleavage and Packaging Proteins
(East Carolina University, 1999-02)Herpes simplex virus (HSV) DNA is cleaved from concatemers and packaged into capsids in infected cell nuclei. This process requires seven viral proteins, including UL15 and UL28. UL15 expressed alone displays a nuclear ... -
PI(4,5)P2 concentration at the APC side of the Immunological Synapse is Required for Effector T cell Function
(East Carolina University, 2009-05-01)Little is known about the signaling that occurs in an antigen presenting cell (APC) during contact with a T cell. Here we report the concentration of the signaling lipid, PI(4,5)P2, at the APC side of the immunological ... -
PI3K activation is associated with intracellular sodium/iodide symporter protein expression in breast cancer
(East Carolina University, 2007-07-25)Background: The sodium/iodide symporter (NIS) is a membrane glycoprotein mediating active iodide uptake in the thyroid gland and is the molecular basis for radioiodide imaging and therapeutic ablation of thyroid carcinomas. ... -
A Pilot Study: The Effect of Healing Touch on Anxiety, Stress, Pain, Pain Medication Usage, and Physiological Measures in Hospitalized Sickle Cell Disease Adults Experiencing a Vaso-occlusive Pain Episode.
(East Carolina University, 2010)Sickle cell disease (SCD), a common genetic blood disorder affecting primarily African-Americans (Edwards, Scales, Loughlin, Bennett, Harris-Peterson, et al., 2005) causes a vaso-occlusive pain episode (VOPE) affecting ...