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The contribution of motility and chemotaxis in the Borrelia burgdorferi infectious life cycle
(East Carolina University, 2013)Lyme disease has emerged as an increasing problem for people in the east and northeastern part of the United States. It can cause a chronic debilitating infection if left untreated and is difficult to diagnose. The illness ... -
Control of Vascular Smooth Muscle Cell Growth by Connexin 43
(2012-06)Connexin 43 (Cx43), the principal gap junction protein in vascular smooth muscle cells (VSMCs), regulates movement of ions and other signaling molecules through gap junction intercellular communication (GJIC) and plays ... -
Cooperative Effects of Akt-1 and Raf-1 on the Induction of Cellular Senescence in Doxorubicin or Tamoxifen Treated Breast Cancer Cells
(2011-08)Escape from cellular senescence induction is a potent mechanism for chemoresistance. Cellular senescence can be induced in breast cancer cell lines by the removal of estrogen signaling with tamoxifen or by the accumulation ... -
Coronary Artery Calcium Scores: Current Thinking and Clinical Applications
(East Carolina University, 2008-09)Most incident coronary disease occurs in previously asymptomatic individuals who were considered to be at a lower risk by traditional screening methods. There is a definite advantage if these individuals could be reclassified ... -
Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction
(2011)Mouse models are a valuable tool for studying acute injury and chronic remodeling of the myocardium in vivo. With the advent of genetic modifications to the whole organism or the myocardium and an array of biological and/or ... -
Correction:Peer chart audits: A tool to meet Accreditation Council on Graduate Medical Education (ACGME) competency in practice-based learning and improvement
(East Carolina University, 2007-07-27)Background: The Accreditation Council on Graduate Medical Education (ACGME) supports chart audit as a method to track competency in Practice-Based Learning and Improvement. We examined whether peer chart audits performed ... -
Correlation of pretreatment drug induced apoptosis in ovarian cancer cells with patient survival and clinical response
(2012)Background This study was performed to determine if a chemotherapy-induced apoptosis assay (MiCK) could predict the best therapy for patients with ovarian cancer. Methods A prospective, multi-institutional and blinded ... -
Correlation of the National Emergency Medicine M4 Clerkship Examination with USMLE Examination Performance
(2015-12)NTRODUCTION: Assessment of medical students' knowledge in clinical settings is complex yet essential to the learning process. Clinical clerkships use various types of written examinations to objectively test medical ... -
Correlation of the NBME Advanced Clinical Examination in EM and the National EM M4 exams
(2015-01)Introduction Since 2011 two online, validated exams for fourth-year emergency medicine (EM) students have been available (National EM M4 Exams). In 2013 the National Board of Medical Examiners offered the Advanced ... -
Cost Comparison of Foods Purchased for an All-Organic Diet and a Conventional, Non-Organic Diet
(East Carolina University, 2014)The objectives of this study were: To determine if there are mean cost differences between all-organic foods and conventional (non-organic) foods; to determine if there are differences in the mean cost of all-organic foods ... -
Counselors’ Attitudes Toward Sex Trafficking: A Quantitative, National Analysis
(East Carolina University, 2022-06-03)For more than 20 years, the pervasive problem of sex trafficking has garnered increasing attention in research, advocacy, and legislation. The cumulative research focuses on the trafficking of women and girls based on the ... -
Counselors’ Attitudes Toward Sex Trafficking: A Quantitative, National Analysis
(East Carolina University, 2022-06-03)For more than 20 years, the pervasive problem of sex trafficking has garnered increasing attention in research, advocacy, and legislation. The cumulative research focuses on the trafficking of women and girls based on the ... -
Course of Depressive Symptoms and Treatment in the Longitudinal Assessment of Bariatric Surgery (LABS-2) Study
(2014-05)Objective To examine changes in depressive symptoms and treatment in the first three years following bariatric surgery. Design and Methods The Longitudinal Assessment of Bariatric Surgery-2 is an observational ...