Browsing Health Sciences Campus by Author "Baden, Daniel G."
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The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes
Sayer, Andrew; Hu, Qing; Bourdelais, Andrea J.; Baden, Daniel G.; Gibson, James E. (East Carolina University, 2005-11)Brevenal is a nontoxic short-chain trans-syn polyether that competes with brevetoxin (PbTx) for the active site on voltage-sensitive sodium channels. The PbTxs are highly potent polyether toxins produced during blooms of ... -
The inhibition of CHO-K1-BH4 cell proliferation and induction of chromosomal aberrations by brevetoxins in vitro
Sayer, A. N.; Hu, Q.; Bourdelais, Andrea J.; Baden, Daniel G.; Gibson, James E. (East Carolina University, 2006-07)Brevetoxins (PbTxs) are highly potent trans-syn polyether neurotoxins produced during blooms of several species of marine dinoflagellates, most notably Karenia brevis. These neurotoxins act on voltage-sensitive sodium ...