Browsing Health Sciences Campus by Author "Edidin, Michael"
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PI(4,5)P2 concentration at the APC side of the Immunological Synapse is Required for Effector T cell Function
Fooksman, David Robert; Shaikh, Saame Raza; Boyle, Sarah; Edidin, Michael (East Carolina University, 2009-05-01)Little is known about the signaling that occurs in an antigen presenting cell (APC) during contact with a T cell. Here we report the concentration of the signaling lipid, PI(4,5)P2, at the APC side of the immunological ...