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Selective Recruitment of Germ Cell mRNAs by eIF4 Factors
(East Carolina University, 1/13/16)
During germ line development critical steps in the proliferation and differentiation of stem cells into oocytes and sperm are regulated by mRNA translational control. This regulation changes the subset of proteins being ...
Multiple Translation Factor eIF4G (IFG-1) Isoforms are Required for the Apoptosome-Dependent Activation of Germ Cell Apoptosis
(East Carolina University, 2010)
Apoptosis is a naturally occurring process during animal development required for the programmed killing and removal of injured cells. Cellular insult induces a switch in translation that allows for the rapid synthesis ...