Browsing Brody School of Medicine by Title
Now showing items 1443-1462 of 1483
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The UHS Nutrition Initiative: Enhancing the ability of patients, employees and the community to "Eat Smart and Move More"
(2005)This article describes the obesity problem in eastern North Carolina and the responses that the Pitt County Memorial Hospital is taking locally to change policies and environments. -
Understanding the Molecular Mechanisms that Contribute to Parkinson’s Disease: Defining the Role of Ca2+ in TG2: α-synuclein Macromolecular Complex Assembly
(East Carolina University, 2018-12-10)Transglutaminase 2 (TG2) is an allosteric enzyme ubiquitously expressed in human tissue. This versatile enzyme has both Ca2+ -dependent, transamidase and GTPase activities. TG2's Ca2+ -dependent transamidase activity is ... -
The unique roles of IFE-1, a germline-specific isoform of eukaryotic translation factor 4E, during gametogenesis
(East Carolina University, 2009)Fertility and embryonic viability are measures of efficient germ cell growth and differentiation. During oogenesis, spermatogenesis and embryogenesis cells initially proliferate then differentiate into specific tissues. ... -
Unique V3 Loop Sequence Derived from the R2 Strain of HIV-Type 1 Elicits Broad Neutralizing Antibodies
(East Carolina University, 2004-11)DNA vaccines expressing the envelope (Env) of the human immunodeficiency virus type 1 (HIV-1) have been relatively ineffective at generating high-titer, long-lasting, neutralizing antibodies. In this study, DNA vaccines ... -
Unusual Cause of Hepatic Vein Systolic Flow Reversal
(2022-01-26) -
An Unusual Presentation of a Posterior Mediastinal Schwannoma Associated with Traumatic Hemothorax
(2015)Schwannomas of the thoracic cavity are typically an asymptomatic, benign neurogenic neoplasm of the posterior mediastinum. In this case, we present a traumatic hemothorax as the initial presentation for a previously ... -
Unusual reticulin staining pattern in well-differentiated hepatocellular carcinoma
(2011)Background Special stains, such as reticulin stain and CD34 immunostain, are very helpful in the diagnosis of well differentiated hepatocellular carcinoma (HCC). Most studies have shown that absent or decreased reticulin ... -
An update on mindfulness meditation as a self-help treatment for anxiety and depression
(2012)In recent years, complementary and alternative medicine (CAM) treatments have increased in popularity. This is especially true for treatments that are related to exercise and mindfulness-based interventions (MBIs) in the ... -
Upregulation of Human T-Cell Leukemia Virus Type 1 Antisense Transcription by the Viral Tax Protein
(East Carolina University, 2009-02)Several studies have recently demonstrated the existence of human T-cell leukemia virus type 1 (HTLV-1) antisense transcripts, which allow the synthesis of the newly described HBZ protein. Although previous reports have ... -
Urinary Incontinence Before and After Bariatric Surgery
(2015-08-01) -
Use of monoamine oxidase and redox enzymes in atrial tissue as novel predictors of postoperative atrial fibrillation
(East Carolina University, 2014)Postoperative atrial fibrillation (POAF) occurs in approximately 30% of cardiac surgery patients. The complication occurs despite advances in surgical procedures. It is associated with increased mortality, morbidity, and ... -
Using death to one's advantage: HIV modulation of apoptosis
(East Carolina University, 2001-03)Infection by human immunodeficiency virus (HIV) is associated with an early immune dysfunction and progressive destruction of CD4+ T lymphocytes. This progressive disappearance of T cells leads to a lack of immune control ... -
Using TIRF microscopy to analyze stimulated and basal state B-cell MHC II clustering in response to ageing and dietary fish oil
(East Carolina University, 2013)This research focused on developing an efficient TIRF microscopy approach to evaluate membrane protein organization. More specifically, the data demonstrate that TIRF microscopy can detect changes in ex vivo B-cell MHC II ... -
Utilizing Metabolomics and Proteomics for Clinical Applications
(East Carolina University, 2020-11-03)Medical conditions such as heart failure and infant outcomes related to in utero drug exposure have become prevalent amongst the world population. As we observe alarming trends in poor health choices, treating these ... -
VACCINIA VIRUS O1L VIRULENCE GENE AND PROTEIN LOCALIZATION
(2015)Smallpox killed an estimated 500 million people in the twentieth century alone. Although this fatal disease was eradicated from the world over thirty years ago, its potential use as a bioterrorism agent remains a concern. ...