Search
Now showing items 211-220 of 223
Base-By-Base: Single nucleotide-level analysis of whole viral genome alignments
(East Carolina University, 2004-07-14)
Background: With ever increasing numbers of closely related virus genomes being sequenced, it has become desirable to be able to compare two genomes at a level more detailed than gene content because two strains of an ...
The UHS Nutrition Initiative: Enhancing the ability of patients, employees and the community to "Eat Smart and Move More"
(2005)
This article describes the obesity problem in eastern North Carolina and the responses that the Pitt County Memorial Hospital is taking locally to change policies and environments.
Apigenin Prevents UVB-Induced Cyclooxygenase 2 Expression: Coupled mRNA Stabilization and Translational Inhibition
(East Carolina University, 2007-01)
Cyclooxygenase 2 (COX-2) is a key enzyme in the conversion of arachidonic acid to prostaglandins, and COX-2 overexpression plays an important role in carcinogenesis. Exposure to UVB strongly increased COX-2 protein expression ...
Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal
(East Carolina University, 2006-08-22)
Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be dusrupted. Patients infected with HIV or addicted to drugs ...
The Actin Binding Protein, Fesselin, is a Member of the Synaptopodin Family
(East Carolina University, 2008-07)
Fesselin is a natively unfolded protein that is abundant in avian smooth muscle. Like many natively
unfolded proteins, fesselin has multiple binding partners including actin, myosin, calmodulin and
α-actinin. Fesselin ...
Ca2+ and Ionic Strength Dependencies of S1-ADP Binding to Actin-Tropomyosin-Troponin: Regulatory Implications
(East Carolina University, 2004-09)
Skeletal and cardiac muscle contraction are inhibited by the actin-associated complex of tropomyosin-troponin. Binding of Ca21 to troponin or binding of ATP-free myosin to actin reverses this inhibition. Ca21 and ATP-free ...
Bone marrow stromal cells attenuate sepsis via prostaglandin E2— dependent reprogramming of host macrophages to increase their interleukin-10 production
(East Carolina University, 2009-01)
Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed. Administering bone marrow stromal cells (BMSCs—also known as mesenchymal stem cells) to mice before or shortly after inducing sepsis ...
The Brucella abortus Cu,Zn Superoxide Dismutase Is Required for Optimal Resistance to Oxidative Killing by Murine Macrophages and Wild-Type Virulence in Experimentally Infected Mice
(East Carolina University, 2005-05)
Two-dimensional gel electrophoretic analysis of cell lysates from Brucella abortus 2308 and the isogenic hfq mutant Hfq3 revealed that the RNA binding protein Hfq (also known as host factor I or HF-I) is required for the ...
Take Off 4-Health Healthy Lifestyle Camp Nutrition Education Curriculum
(2009-06-09)
Summer camps designed to produce weight loss are popular childhood obesity interventions. Nutrition education is a critical component of youth weight loss camps and we will present the curriculum developed for a 3 week ...
Using death to one's advantage: HIV modulation of apoptosis
(East Carolina University, 2001-03)
Infection by human immunodeficiency virus (HIV) is associated with an early immune dysfunction and progressive destruction of CD4+ T lymphocytes. This progressive disappearance of T cells leads to a lack of immune control ...