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The role of the proximal small intestine in improvements in diabetes resolution and insulin sensitivity following bariatric surgery in type 2 diabetes
(East Carolina University, 2011)
Bariatric surgery is an effective, rapid, and durable treatment for obesity and type 2 diabetes mellitus (T2DM). Roux-en Y Gastric Bypass (RYGB) resolves T2DM in 80% of cases, while gastric banding (LAGB) resolves T2DM in ...
The Pong Principle
(2011-02-25)
"Learning to Listen: A Patient Becomes the Teacher By Serving Up Life-Changing Advice
CD44 and hyaluronan promote the bmp7 signaling response in chondrocytes
(East Carolina University, 2011)
Cell-matrix interactions are important in maintaining cartilage homeostasis. Hyaluronan binding to its principal receptor CD44 is essential for such interactions. Hyaluronan-CD44 interactions are required for the retention ...
Investigations into the roles of bacteroides fragilis thioredoxins during the oxidative stress response
(East Carolina University, 2011)
The Gram-negative Bacteroides fragilis is the most frequently isolated bacterium from anaerobic infections. Native to the human intestinal tract, it serves a symbiotic role breaking down complex polysaccharides and ...
Regulation of KSHV replication by glycoprotein B: chronicles of a virus and its host
(East Carolina University, 2011)
Kaposi's sarcoma-associated herpesvirus (KSHV), the causative agent of three cancers: Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and the plasmablastic form of multicentric Castleman disease (MCD), shares many ...
Glycemic Control Patterns and Kidney Disease Progression among Primary Care Patients with Diabetes Mellitus
(2011-07)
Background: Reducing glycosylated hemoglobin (HbA1c) to near or less than 7% in patients with diabetes is associated with diminished microvascular complications, but this level is not consistently achieved. The purpose of ...
p53 and NGAL: dual regulatory roles in advanced prostate cancer
(East Carolina University, 2011)
The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ...
Helping Hands: A Guidebook for Volunteer Meal Providers
(2011-09-27)
Helping Hands: A Guidebook for Volunteer Meal Providers
Author(s): J. Jennings,1 R. Ward,2 K. Kolasa3; 1Nutrition Science, East Carolina University, Greenville, NC, 2East Carolina University, Greenville, NC, 3Family ...
DINITROBENZENES STIMULATE ELECTRON FLUX WITHIN NEURONAL NITRIC OXIDE SYNTHASE IN THE ABSENCE OF CALMODULIN
(2011)
Efficient electron transfer and conversion of L-arginine to L-citrulline and nitric oxide
(NO●) by neuronal nitric oxide synthase (nNOS) requires calmodulin (CaM) binding. The
present study focused on electron transfer ...
Fine Particulate air Pollution is Associated with Higher Vulnerability to Atrial Fibrillation—The APACR Study
(2011-04)
The acute effects and the time course of fine particulate pollution (PM2.5) on atrial fibrillation/flutter (AF) predictors, including P-wave duration, PR interval duration, and P-wave complexity, were investigated in a ...