Browsing Anatomy and Cell Biology by Subject "PP1"
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PPP1R2 COORDINATES KINASE AND PHOSPHATASE ACTIVITY TO REGULATE THE CENTROSOME AND MIDBODY
(East Carolina University, 2021-04-21)Centrosomes are the primary microtubule organizing centers of the cell and prepare the cell for division by establishing the bipolar spindle during mitosis. A balance of kinase and phosphatase activity regulates centrosome ... -
PPP1R42 is a positive regulator of PP1 in centrosome duplication and separation and cilia dynamics
(East Carolina University, 2014)The centrosome is a dynamic structure that undergoes structural and functional transitions, which are coordinated with the cell cycle. It functions as the microtubule organizing center (MTOC) in interphase, duplicates and ...