Browsing Internal Medicine by Author "DeVente, James E."
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MCF-7 breast cancer cells transfected with protein kinase C-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype.
Ways, D. Kirk; Kukoly, Cynthia A.; DeVente, James E.; Hooker, Jerry L.; Bryant, Winifred O.; Posekany, Karla J.; Fletcher, Donald J.; Cook, Paul P.; Parker, Peter J. (East Carolina University, 1995-04)Increased protein kinase C (PKC) activity in malignant breast tissue and positive correlations between PKC activity and expression of a more aggressive phenotype in breast cancer cell lines suggest a role for this signal ...