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MCF-7 breast cancer cells transfected with protein kinase C-alpha exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype.
(East Carolina University, 1995-04)
Increased protein kinase C (PKC) activity in malignant breast tissue and positive correlations between PKC activity and expression of a more aggressive phenotype in breast cancer cell lines suggest a role for this signal ...
Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death.
(East Carolina University, 1995-10)
Protein kinase C (PKC) modulates growth, differentiation, and apoptosis in a cell-specific fashion. Overexpression of PKC-a in MCF-7 breast cancer cells (MCF-7-PKC-a cell) leads to expression of a more transformed phenotype. ...
Postvaccinial (influenza) disseminated encephalopathy (Brown-Sequard syndrome).
(East Carolina University, 1995-09)
This article reports a case of Brown-Sequard syndrome that occurred in a patient following the administration of trivalent influenza vaccine. The patient responded well to intravenous steroids and physical therapy. This ...
The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad.
(East Carolina University, 1997-03)
The mouse hind footpad inoculation model has served as a standard laboratory system for the study of the neuropathogenesis of herpes simplex virus type 1 (HSV-1) infection. The temporal and spatial distribution of viral ...