Browsing by Title
Now showing items 258-277 of 10625
-
Accomplished Teaching, Learning and Schools (ATLAS)
(2016-01-01)The Accomplished Teaching, Learning and Schools (ATLAS) database is a valuable teaching tool that takes some of the mystery out of the National Board for Professional Teaching Standards certification process, and provides ... -
ACCOUNTING STUDENTS’ PERCEPTION VS. REALITY OF STRESS IN ACCOUNTING
(East Carolina University, 2023-04-26)The accounting industry is typically perceived as stressful with studies dating back to the 1950s describing occupational stress in the field (Smith, 1990). This is evident today when looking at the high employee turnover ... -
Accumulated Cyclone Energy and Tropical Cyclone Tracks: An In-Depth Analysis of the Anomalously Inactive 2013 Atlantic Hurricane Season
(2015)The 2013 season was forecast by the National Oceanic and Atmospheric Administration (NOAA) Climate Prediction Center (and many other seasonal forecast centers) to be much more active in terms of tropical cyclone activity ... -
ACCUMULATION OF ORGANOPHOSPHATE PESTICIDES IN PORCINE TISSUE OF PIGS RAISED IN EASTERN NORTH CAROLINA: ANALYSIS BY MALDI-TOF-MS
(East Carolina University, 2019-05-02)The incidence rate of diabetes and obesity is increasing each year, as well as organophosphate pesticides (OPs) in the United States. OPs are toxic and can cause numerous acute effects, but the long-term chronic exposure ... -
Accuracy of the SenseWear Pro ArmbandTM During Short Bouts of Exercise
(East Carolina University, 2016-04-28)Due to the limitations of traditional metabolic measuring systems and other devices used to measure energy expenditure, new technologies that are more mobile and comfortable are being designed for use in the physical ... -
Accuracy of Wet Bulb Globe Temperature (WBGT) Obtained from Regional Weather Station Data for Agricultural Settings in Eastern North Carolina as Proxy for WBGT Obtained from Local Heat Stress Monitors
(East Carolina University, 2022-12-01)Introduction: Agricultural workers are at high risk of suffering from heat stress and subsequently developing heat-related illnesses (HRIs) due to the outdoor nature of their work. This risk can be exacerbated in hot, ... -
ACE's and Friendship Difficulties
(East Carolina University, 2022-05-04)Adverse childhood experiences (ACEs) are traumatic events in an individual’s life that occurred before age 18. Examples of ACEs include various types of abuse, neglect, and household dysfunction. Decades of research on the ... -
Acid ceramidase is upregulated in AML and represents a novel therapeutic target
(2016-12-13)There is an urgent unmet need for new therapeutics in acute myeloid leukemia (AML) as standard therapy has not changed in the past three decades and outcome remains poor for most patients. Sphingolipid dysregulation through ... -
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
(2013-10)The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ... -
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
(2013-12-05)The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ... -
Acidosis Activated GPR68 Promotes Vascular Smooth Muscle Cell Growth
(East Carolina University, 2020-12-17)Cardiovascular disease (CVD) is the primary cause of death in the United States and worldwide. Localized extracellular acidosis has been theorized as a possible contributor to CVD pathogenesis, but its precise impact remains ... -
Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells
(2017-01-27)Acidosis commonly exists in the tissue microenvironment of various pathophysiological conditions such as tumors, inflammation, ischemia, metabolic disease, and respiratory disease. For instance, the tumor microenvironment ... -
Acidosis Activation of the Proton-Sensing GPR4 Receptor Stimulates Vascular Endothelial Cell Inflammatory Responses Revealed by Transcriptome Analysis
(2013)Acidic tissue microenvironment commonly exists in inflammatory diseases, tumors, ischemic organs, sickle cell disease, and many other pathological conditions due to hypoxia, glycolytic cell metabolism and deficient blood ... -
Acidosis Decreases c-Myc Oncogene Expression in Human Lymphoma Cells: A Role for the Proton-Sensing G Protein-Coupled Receptor TDAG8
(2013-10)Acidosis is a biochemical hallmark of the tumor microenvironment. Here, we report that acute acidosis decreases c-Myc oncogene expression in U937 human lymphoma cells. The level of c-Myc transcripts, but not mRNA or protein ...