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Now showing items 1-20 of 4931
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DEVELOPMENT OF SMALL-MODELCULE INHIGITORS OF THE INTIATING PROTEASES, C1r AND C1s, OF THE CLASSICAL COMPLEMENT PATHWAY
(2019-12)Complement is a proteolytic cascade that upon activation plays a key effector role in the innate immune system and acts to prime the adaptive immune response. During normal homeostatic events, complement is tightly regulated ... -
YIELD STRENGTH OF THE EGADI 10 WARSHIP: USING NONLINEAR COMPUTER SIMULATIONS TO EXAMINE COLLISION DYNAMICS IN GRECO-ROMAN NAVAL CONFLICTS
(2019-12)The study of ancient Mediterranean naval warfare expanded dramatically with the emergence of maritime archaeology and the subsequent discovery of artifacts and ship remains such as the Athlit and Egadi rams. The ship ... -
“LIFE HUNG ON A WORD”: SHIBBOLETHS AND GENOCIDE IN DANTICAT’S THE FARMING OF BONES, WIESEL’S NIGHT, AND COURTEMANCHE’S A SUNDAY AT THE POOL IN KIGALI
(2019-12)This thesis explores how shibboleths, or cultural passwords, function as markers to signify identity and group membership status among coexisting ethnic groups. Specifically, shibboleths are critical for identity detection ... -
A SINGLE-CHAIN GMCSF-MOG TOLEROGENIC VACCINE EXPANDS MOG-SPECIFIC CD25+ FOXP3+ REGULATORY T CELLS THROUGH LOW-EFFICIENCY ANTIGEN RECOGNITION EVENTS TO INHIBIT EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(2019-12)Previous studies showed that tolerogenic vaccines comprised of single-chain GMCSF-neuroantigen (NAg) fusion proteins inhibited experimental autoimmune encephalomyelitis (EAE) in rodents. The studies detailed here provide ... -
ACTING "WHITE": THE UNSPOKEN, UNDERSTOOD HIERARCHY OF BLACKNESS
(2020-01-09)This thesis will examine how a variety of extenuating factors serve to complicate a black person’s self-identity, as well as determine acceptance or exclusion from the black community in the United States. The introductory ... -
Circular Single-Stranded DNA Virus (Microviridae: Gokushovirinae: Jodiemicrovirus) Associated with the Pathobiome of the Flat-Back Mud Crab, Eurypanopeus depressus
(2019-11-21)A single-stranded DNA (ssDNA) virus is presented from a metagenomic data set derived from Alphaproteobacteria-infected hepatopancreatic tissues of the crab Eurypanopeus depressus. The circular virus genome (4,768 bp) encodes ... -
I want to survive and thrive: diet and physical activity recommendations for Breast Cancer Survivors
(2018-09)In this article, we review current diet and physical activity recommendations for long-time survivors of breast cancer. We also hear the voice of a survivor and her response to the diagnosis of a postmenopausal breast ... -
Life in a contaminant milieu: PPCP mixtures generate unpredictable outcomes across trophic levels and life stagest
(2019-12-05)Nearly all aquatic ecosystems are affected by sublethal levels of anthropogenic chemical contamination, but other agents of large‐scale anthropogenic disruption of ecosystems have received more attention. Consequently, ... -
Differential gene expression and gene variants drive color and pattern development in divergent color morphs of a mimetic poison frog
(2019-07-21)Evolutionary biologists have long investigated the ecological contexts, evolutionary forces, and proximate mechanisms that produce the diversity of animal coloration we see in the natural world. In aposematic species, color ... -
Customer Reviews Analysis With Deep Neural Networks for E-Commerce Recommender Systems
(2019-08-26)An essential prerequisite of an effective recommender system is providing helpful information regarding users and items to generate high-quality recommendations. Written customer review is a rich source of information ... -
MELPF Version 1: Modeling Error Learning Based Post-Processor Framework for Hydrologic Models Accuracy Improvement
(2019-09-23)This paper studies how to improve the accuracy of hydrologic models using machine-learning models as postprocessors and presents possibilities to reduce the workload to create an accurate hydrologic model by removing the ... -
Construction of realistic hybrid computational fetal phantoms from radiological images in three gestational ages for radiation dosimetry applications
(2019-10-10)Radiation exposure and associated radiation risks are major concerns for fetal development for pregnant patients who undergo radiation therapy or diagnostic imaging procedures. In order to accurately estimate the radiation ... -
Imaging of morphological and biochemical hallmarks of apoptosis with optimized optogenetic tools
(2019-10-03)Creation of optogenetic switches for specific activation of cell death pathways can provide insights into apoptosis and could also form a basis for noninvasive, next-generation therapeutic strategies. Previous work has ... -
Developing high performance concrete for precast/prestressed concrete industry
(2019-12)High performance concrete (HPC) is a new class of concrete that has superior characteristics compared to conventional concrete. Despite of its superior characteristics, HPC is not widely used in local and international ... -
Measuring Workplace Discrimination among Sexual and Gender Minority Workers
(2019-11-01)As inequities in health for sexual and gender minority (SGM; eg, lesbian, gay, bisexual, and transgender [LGBT]) populations become increasingly well documented, it is important to investigate causes of inequities to ... -
QUALITY IMPROVEMENT INITIATIVE TO INCREASE THE NUMBER OF REFERRALS TO DIABETES EDUCATION
(2019-12-12)Diabetes is a nationwide health concern and the seventh leading cause of death in the Unites States. The disease and its complications negatively impact the health of the patients and increase health care costs. As a chronic ... -
An endemic plant and the plant-insect visitor network of a dune ecosystem
(2019-04)Network theory increasingly is used to quantify and evaluate mutualistic interactions, such as those among plants and their flower-visiting insects or pollinators. Some plant species have been shown to be important in ... -
Provider Prompting to Improve Colorectal Cancer Screening Rates
(2019-12-04)Colorectal cancer (CRC) screening is recommended for average risk adults aged 50 to 75 years. Healthy People 2020 objectives include reducing new cancer cases and the illness, disability, and deaths secondary to cancer. ... -
Hypertension Treatment Adherence with 3-D Models
(2019-12-04)Hypertension treatment adherence is a significant issue in the United States. Almost half of patients with diagnosed hypertension are non-adherent with medications and/or diet and appointment keeping with their provider. ... -
Standardized Postpartum Depression Screening of NICU Mothers
(2019-12-04)The purpose of this QI project was to determine the feasibility of instituting a standardized postpartum depression screening guideline in the NICU. A draft guideline was developed that instructed medical providers to ...