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ACCUMULATION OF ORGANOPHOSPHATE PESTICIDES IN PORCINE TISSUE OF PIGS RAISED IN EASTERN NORTH CAROLINA: ANALYSIS BY MALDI-TOF-MS
(East Carolina University, 2019-05-02)The incidence rate of diabetes and obesity is increasing each year, as well as organophosphate pesticides (OPs) in the United States. OPs are toxic and can cause numerous acute effects, but the long-term chronic exposure ... -
Accuracy of the SenseWear Pro ArmbandTM During Short Bouts of Exercise
(East Carolina University, 2016-04-28)Due to the limitations of traditional metabolic measuring systems and other devices used to measure energy expenditure, new technologies that are more mobile and comfortable are being designed for use in the physical ... -
Accuracy of Wet Bulb Globe Temperature (WBGT) Obtained from Regional Weather Station Data for Agricultural Settings in Eastern North Carolina as Proxy for WBGT Obtained from Local Heat Stress Monitors
(East Carolina University, 2022-12-01)Introduction: Agricultural workers are at high risk of suffering from heat stress and subsequently developing heat-related illnesses (HRIs) due to the outdoor nature of their work. This risk can be exacerbated in hot, ... -
ACE's and Friendship Difficulties
(East Carolina University, 2022-05-04)Adverse childhood experiences (ACEs) are traumatic events in an individual’s life that occurred before age 18. Examples of ACEs include various types of abuse, neglect, and household dysfunction. Decades of research on the ... -
Acid ceramidase is upregulated in AML and represents a novel therapeutic target
(2016-12-13)There is an urgent unmet need for new therapeutics in acute myeloid leukemia (AML) as standard therapy has not changed in the past three decades and outcome remains poor for most patients. Sphingolipid dysregulation through ... -
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
(2013-10)The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ... -
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
(2013-12-05)The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ... -
Acidosis Activated GPR68 Promotes Vascular Smooth Muscle Cell Growth
(East Carolina University, 2020-12-17)Cardiovascular disease (CVD) is the primary cause of death in the United States and worldwide. Localized extracellular acidosis has been theorized as a possible contributor to CVD pathogenesis, but its precise impact remains ... -
Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells
(2017-01-27)Acidosis commonly exists in the tissue microenvironment of various pathophysiological conditions such as tumors, inflammation, ischemia, metabolic disease, and respiratory disease. For instance, the tumor microenvironment ... -
Acidosis Activation of the Proton-Sensing GPR4 Receptor Stimulates Vascular Endothelial Cell Inflammatory Responses Revealed by Transcriptome Analysis
(2013)Acidic tissue microenvironment commonly exists in inflammatory diseases, tumors, ischemic organs, sickle cell disease, and many other pathological conditions due to hypoxia, glycolytic cell metabolism and deficient blood ... -
Acidosis Decreases c-Myc Oncogene Expression in Human Lymphoma Cells: A Role for the Proton-Sensing G Protein-Coupled Receptor TDAG8
(2013-10)Acidosis is a biochemical hallmark of the tumor microenvironment. Here, we report that acute acidosis decreases c-Myc oncogene expression in U937 human lymphoma cells. The level of c-Myc transcripts, but not mRNA or protein ... -
Acquiring Articles through Unmediated, User-Initiated Pay-Per-View Transactions: An Assessment of Current Practices
(East Carolina University, 2009-12)Depressed economic times often lead libraries to consider new practices, including alternatives to the traditional subscription model. This column discusses a pay-per-view (PPV) model for acquiring journal articles whereby ... -
The Acquisition of a Plastid by Haptophytes, Cryptophytes, and Photosynthetic Heterokonts
(East Carolina University, 2014)Red algae and green plants are known to have obtained their photosynthetic organelles, or plastids, through the endosymbiotic adoption of cyanobacteria. It is still widely debated as to how other eukaryotic alga such as ... -
Acquisition of Financial Education Among College Students: How Attitudes and Future Expectations Shape Desire for Personal Finance Educatio
(East Carolina University, 2018-05-24)This study used a sample of undergraduate students at a public university to determine students’ interest in and views of personal finance. Students who were surveyed responded that personal finance topics are important, ... -
THE ACQUISITION OF NEW STUDENT AFFAIRS PROFESSIONALS' BELIEFS AND PERCEPTIONS ABOUT FACULTY
(East Carolina University, 2013)The purpose of this study is to better understand how new student affairs professionals acquire their beliefs and perceptions about faculty. This study originates from a conceptual framework that includes: (1) a call for ...