Browsing by Author "Biomedical Sciences"
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The Immunotoxicity of Two Novel Perfluoroether Acids Found in North Carolina’s Cape Fear River
Tobin, Emma E (East Carolina University, 2021-08-02)Novel perfluoroether acids (PFEAs) have been identified in surface waters of North Carolina and in the blood of some North Carolina residents. As some per- and polyfluoroalkyl substances (PFAS) are presumed immune hazards ... -
The Role of the Notch-3 Receptor in Stemness, EMT, and Tumorigenesis in Colorectal Cancer
Vinson, Kaitlyn E. (East Carolina University, 2016-05-05)As the second leading cause of cancer death worldwide, colorectal cancer (CRC) poses a significant threat to both men and women alike. Although a small percentage of CRC cases are inherited, the majority of cases arise ... -
TMEFF2 is an epigenetic modulator that promotes androgen independent growth in castration-resistant prostate cancer cells
Corbin, Joshua Moses (East Carolina University, 2014)While the ability to detect PCa has improved significantly due to PSA screenings, the survival rate for men diagnosed with PCa has remained stagnant, and the disease remains the second leading cause of cancer related deaths ... -
Use of monoamine oxidase and redox enzymes in atrial tissue as novel predictors of postoperative atrial fibrillation
Darden, Timothy M. (East Carolina University, 2014)Postoperative atrial fibrillation (POAF) occurs in approximately 30% of cardiac surgery patients. The complication occurs despite advances in surgical procedures. It is associated with increased mortality, morbidity, and ... -
Using TIRF microscopy to analyze stimulated and basal state B-cell MHC II clustering in response to ageing and dietary fish oil
Melton, Mark T. (East Carolina University, 2013)This research focused on developing an efficient TIRF microscopy approach to evaluate membrane protein organization. More specifically, the data demonstrate that TIRF microscopy can detect changes in ex vivo B-cell MHC II ...