Browsing by Author "Biology"
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Investigating the Impact of Mettl16 Cellular Localization on RNA Binding Preferences
Nance, Daniel Joel (East Carolina University, 2019-05-14)Recently, mRNA modification by N6-methyladenosine (m6A) has been shown to be involved in post-transcriptional regulation processes including mRNA stability, splicing and promotion of translation. Accordingly, the mRNA ... -
Investigating the Interaction of RecQL4 and Mcm10 in Drosophila melanogaster
Rummings, Wayne Anthony, Jr. (East Carolina University, 2014)Accurate duplication and regulation of the eukaryotic genome requires precise coordination among multiple replication factors. RecQL4, the least characterized RecQ protein, is a 1208 amino acid protein containing a centrally ... -
Investigating the Microbial Communities Associated with Aluminum Alloys 2024 and 7075
Price, Kyra A. (East Carolina University, 2020-11-17)Aluminum (Al), one of the most versatile, cost-effective, and appealing metals for use in construction, has no known biological function. Al alloys in aquatic environments provide a surface for attachment and can be ... -
INVESTIGATING THE MOLECULAR CONTROL OF ECDYSONE RESPONSE GENE, E74, IN THE DROSOPHILA OVARY.
Davenport, Lindsay L (East Carolina University, 2017-05-05)Oogenesis is the process by which an egg develops from precursor cells in the ovary. This process has been widely studied; however, many of the molecular mechanisms that regulate oocyte development and growth remain unclear. ... -
Investigating the Relationship between Environmental Lead Exposures and the Onset of Alzheimer's Disease Pathologies
Johnson, Dakota, C (2014)It is been estimated that nearly 5 million Americans suffer from Alzheimer's Disease (AD), making finding its cause one of medicine's top priorities. It has long been known that genetics plays a major role in the development ... -
Investigating the Relationship Between Zetaproteobacteria and Cyanobacteria and its Implications for the Geological Record
Chamberlain, Michelle (East Carolina University, 2022-07-14)Banded Iron Formations (BIFs) are geological relics of the ancient oceans that were partially formed by microorganisms. This includes oxygenic phototrophs and iron-oxidizing bacteria (FeOB) whose relative contributions are ... -
Investigating the Relationship Between Zetaproteobacteria and Cyanobacteria and its Implications for the Geological Record
Chamberlain, Michelle (East Carolina University, 2022-07-14)Banded Iron Formations (BIFs) are geological relics of the ancient oceans that were partially formed by microorganisms. This includes oxygenic phototrophs and iron-oxidizing bacteria (FeOB) whose relative contributions are ... -
Investigating the reproductive migration of adult hickory shad, Alosa mediocris
Murauskas, Joshua Graham. -
Investigating the role microRNAs play in the root-knot nematode Meloidogyne incognita’s viability, reproduction, and parasitism in cotton
Shepherd, Jennings (East Carolina University, 2023-04-25)Functions of four microRNAs (miRNAs), min-miR1, min-miR71, min-miR100a, and min-miR-124, were investigated in the parasitic nematode Meloidogyne incognita’s (M. incognita’s) overall behavior and mortality. M. incognita is ... -
Investigating the Role of Conserved Cysteine Residues in Arabidopsis thaliana Diacylglycerol Acyltransferase 1
Pahl, Matthew (East Carolina University, 2021-07-28)Triacylglycerols (TAGs) are biomolecules found in all organisms comprised of three fatty acid chains esterified to a glycerol backbone. In humans, TAGs are important energy storage reserves whose misregulation are associated ... -
Investigating the role of CRL5, an ubiquitin ligase, in ovarian follicle development.
Hardy, Victoria L (East Carolina University, 2016-07-20)During oogenesis, follicle cells surround maturing oocytes, which produce factors necessary for proper oocyte growth and development. Correct encapsulation of the oocyte by follicle cells is therefore essential for ... -
Investigating the Role of CtBP in Colorectal Cancer
Owens, Ashley Brenna (2015-04-29)Recent studies in breast cancer tissue have demonstrated that C-terminal binding protein (CtBP) over-expression induces stem cell-like features and genome instability; whereas CtBP depletion or caloric restriction reverses ... -
Investigating the Role of Ecdysone Receptor in Germline to Somatic Cell Communication
Swain, Lindsay (East Carolina University, 2023-12-04)Oogenesis requires complex coordination between both somatic and germ cell populations, relying on systemic signals such as hormones for proper oocyte production and formation. Drosophila melanogaster is an excellent model ... -
Investigating the role of soil legacy effects and community engagement in the management of Lespedeza cuneata, an invasive legume
Hodges, Matthew Steven (East Carolina University, 2020-11-23)Invasive plant species present a growing threat to biodiversity. Many invasive plants are able to recruit microbial symbionts in their novel range and establish plant-soil feedbacks that influence growth and fitness. These ... -
Investigating the role of TER94 in Drosophila melanogaster germ cells
Gowdy, Alyssa Celine (East Carolina University, 2021-05-28)Mutations in Valosin-Containing Protein (VCP) can lead to onset of Amyotrophic Lateral Sclerosis, a fatal neurodegenerative disease; however, the intracellular functions of VCP in cells remain unclear. To study the ... -
Investigating the role of transcription factor, Trl, during germline development in the Drosophila ovary
Davenport, Lindsay L (East Carolina University, 2019-07-22)Oogenesis is the process by which an egg develops from undifferentiated cells in the ovary. The Drosophila melanogaster ovary is an assembly line for egg production, making it a great system to investigate initial oocyte ... -
Investigating the roles of E-T coupling and social environment in the stimulus-dependent expression of parathyroid hormone 2.
Smith, Cameron Paul (East Carolina University, 2021-05-28)In larval zebrafish, parathyroid hormone 2 (pth2) codes for a peptide hormone that is expressed exclusively in cells near the ventral part of the posterior tuberculum, an area of the forebrain involved in sensori-motor ... -
Investigating the Seed Bank of a Wetland Plant Community in a Long-Term Mowing and Fertilization Experiment
Harrelson, Peyton S (East Carolina University, 2023-05-15)The seed bank of a plant community—the store of viable, dormant seeds below the soil surface—holds a legacy of its past composition and may have potential for restoration following habitat degradation. An ongoing 20-year ... -
Investigating the Structural and Functional Roles of Conserved Cysteine Residues in Arabidopsis thaliana Fatty-Acid Desaturase 2
Novotny, Lauren (East Carolina University, 2022-12-06)Plant-generated unsaturated fatty acids (UFAs) and polyunsaturated fatty acids (PUFAs) are vital to a plant's growth and survival through maintenance of plasma membrane fluidity and integrity, in addition to the various ... -
Investigation of conserved cysteines on 6 fatty acid desaturase function in Arabidopsis thaliana
Dave, Parth (East Carolina University, 2021-05-28)Plants are an incredibly diverse group of organisms with over 300,000 species inhabiting different environments worldwide. Recent advances in biotechnology have driven investigations into the biochemical properties of plant ...