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Now showing items 5409-5428 of 10631
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Investigating Intra- and Inter-Molecular Coevolution of Intrinsically Disordered Protein, Prothymosin-alpha
(East Carolina University, 1/13/16)Prothymosin-α (ProTα) is a small, highly acidic protein found in the nuclei of virtually all mammalian tissues. It belongs to a class of proteins known for their lack of a rigid three-dimensional structure called intrinsically ... -
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ... -
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ... -
Investigating Membrane Protection of Red Blood Cells in the Presence of Mono and Disaccharides at Hypothermic Storage Conditions
(East Carolina University, 8/5/2020)The maximum approved storage time of red blood cells under hypothermic conditions is 42 days when treated with an appropriate additive solution. Here, we investigated the possible protective properties of various mono and ... -
Investigating Non-Tight Junction Functions of Claudin-7: Regulating Large Intestine Stem Cell Functions and Niche Maintenance, and Junctional Protein Nanoarchitecture
(East Carolina University, 2022-12-12)Edit this abstract. -
Investigating Novel Chromosome 2 Genetic Variants Associated with Recurrent Stroke
(East Carolina University, 2019-07-18)As the fifth leading cause of death and leading cause of long-term disability, stroke affects 795,000 individuals annually in the United States alone. Recurrent stroke, which is far more deadly and disabling, accounts for ... -
INVESTIGATING SALINITY TOLERANCE AND PARASITE DIVERSITY IN NATIVE NORTH CAROLINA ESTUARY PANOPEIDS (MUD CRABS)
(East Carolina University, 2023-07-11)Investigating organismal response to invasions is increasingly important given human-mediated global change. Estuarine organisms face numerous biotic and abiotic factors that influence their ability to respond to invaders ... -
Investigating Scuba Divers' Attitudes To Sustainable Shipwreck Diving In North Carolina
(East Carolina University, 2015)This study examined the ways in which NC scuba divers identify sustainable shipwreck diving activities to gain a better understanding of how their behavior impacts sustainable cultural tourism on the coast of North Carolina. ... -
Investigating the causes of hatching failure of Eastern Bluebird eggs: A possible role for heat shock proteins
(East Carolina University, 2023-05-03)Eastern Bluebirds (Sialia sialis) studied for 13 years at East Carolina University’s West Research Campus have shown declines in reproductive success via hatching failure in recent years. The purpose of my research is to ... -
INVESTIGATING THE EFFECTS OF LARVAL PHENOTYPES ON TRAITS EXHIBITED AT A CRUCIAL LIFE-HISTORY SWITCH POINT
(East Carolina University, 2017-07-25)In organisms with complex life histories, phenotypes exhibited in non-reproductive life stages are often correlated with adult performance and fitness. For example, in anurans (frogs and toads), age and size at metamorphosis ... -
Investigating the Effects of Sodium Benzoate on Fat Deposition and Pharyngeal Pumping and Related Genetic Mechanism in Caenorhabditis elegans
(East Carolina University, 2022-07-18)Sodium benzoate is a widely used food preservative common in many household products due to its antibacterial and antifungal activities. However, many of its side effects other than as a preservative has been under research ... -
Investigating the Effects of Sodium Benzoate on Fat Deposition, Pharyngeal Pumping, and Related Genetic Mechanisms in Caenorhabditis elegans
(East Carolina University, 2022-07-18)Sodium benzoate is a widely used food preservative common in many household products due to its antibacterial and antifungal activities. However, many of its side effects other than as a preservative has been under research ... -
Investigating the genetic basis of aposematic coloration in poison frogs
(East Carolina University, 2023-11-29)Aposematic organisms rely on their conspicuous appearance to signal that they are defended and unpalatable. Such phenotypes are strongly tied to survival and reproduction. Aposematic colors and patterns are highly variable; ... -
Investigating the genetic interaction between DNA replication proteins Mcm10 and RecQ4 in Drosophila melanogaster
(East Carolina University, 2017-12-12)Necessary to the survival of cellular life is proper replication and maintenance of the genome. Replication proteins Mcm10 and RecQ4 have well-characterized essential roles in assembly, initiation, proper functioning of ... -
Investigating the Impact of Mettl16 Cellular Localization on RNA Binding Preferences
(East Carolina University, 2019-05-14)Recently, mRNA modification by N6-methyladenosine (m6A) has been shown to be involved in post-transcriptional regulation processes including mRNA stability, splicing and promotion of translation. Accordingly, the mRNA ... -
Investigating the Impact of Reader’s Theater on the Prosody Scores of Middle School Students with Disabilities
(2016-04-08)The purpose of this single-subject, pre- and post-test design action research study was to determine how implementing Reader’s Theater as a prosody intervention might impact the prosody scores of middle school students ... -
Investigating the Interaction of RecQL4 and Mcm10 in Drosophila melanogaster
(East Carolina University, 2014)Accurate duplication and regulation of the eukaryotic genome requires precise coordination among multiple replication factors. RecQL4, the least characterized RecQ protein, is a 1208 amino acid protein containing a centrally ... -
Investigating the Microbial Communities Associated with Aluminum Alloys 2024 and 7075
(East Carolina University, 2020-11-17)Aluminum (Al), one of the most versatile, cost-effective, and appealing metals for use in construction, has no known biological function. Al alloys in aquatic environments provide a surface for attachment and can be ... -
INVESTIGATING THE MOLECULAR CONTROL OF ECDYSONE RESPONSE GENE, E74, IN THE DROSOPHILA OVARY.
(East Carolina University, 2017-05-05)Oogenesis is the process by which an egg develops from precursor cells in the ovary. This process has been widely studied; however, many of the molecular mechanisms that regulate oocyte development and growth remain unclear. ...