Browsing by Title
Now showing items 5423-5442 of 10630
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Investigating the Impact of Mettl16 Cellular Localization on RNA Binding Preferences
(East Carolina University, 2019-05-14)Recently, mRNA modification by N6-methyladenosine (m6A) has been shown to be involved in post-transcriptional regulation processes including mRNA stability, splicing and promotion of translation. Accordingly, the mRNA ... -
Investigating the Impact of Reader’s Theater on the Prosody Scores of Middle School Students with Disabilities
(2016-04-08)The purpose of this single-subject, pre- and post-test design action research study was to determine how implementing Reader’s Theater as a prosody intervention might impact the prosody scores of middle school students ... -
Investigating the Interaction of RecQL4 and Mcm10 in Drosophila melanogaster
(East Carolina University, 2014)Accurate duplication and regulation of the eukaryotic genome requires precise coordination among multiple replication factors. RecQL4, the least characterized RecQ protein, is a 1208 amino acid protein containing a centrally ... -
Investigating the Microbial Communities Associated with Aluminum Alloys 2024 and 7075
(East Carolina University, 2020-11-17)Aluminum (Al), one of the most versatile, cost-effective, and appealing metals for use in construction, has no known biological function. Al alloys in aquatic environments provide a surface for attachment and can be ... -
INVESTIGATING THE MOLECULAR CONTROL OF ECDYSONE RESPONSE GENE, E74, IN THE DROSOPHILA OVARY.
(East Carolina University, 2017-05-05)Oogenesis is the process by which an egg develops from precursor cells in the ovary. This process has been widely studied; however, many of the molecular mechanisms that regulate oocyte development and growth remain unclear. ... -
INVESTIGATING THE MOLECULAR MECHANISMS UNDERLYING SKIN FRAGILITY IN TP63-LINKED ECTODERMAL DYSPLASIAS
(East Carolina University, 2022-04-28)Ankyloblepharon-ectodermal defects-cleft lip/palate (AEC) syndrome and ectrodactyly-ectodermal dysplasia-cleft lip/palate (EEC) syndrome are two rare autosomal dominant disorders caused by heterozygous mutations occurring ... -
Investigating the Performance of the Visual Oddball Paradigm in the Context of Facial Recognition
(East Carolina University, 2021-06-03)The sequential visual oddball paradigm is a technique that is often used to elicit various components of cognitive event related potentials (ERPs). These components may serve as reliable biomarkers for neurodegenerative ... -
Investigating the Relationship between Environmental Lead Exposures and the Onset of Alzheimer's Disease Pathologies
(2014)It is been estimated that nearly 5 million Americans suffer from Alzheimer's Disease (AD), making finding its cause one of medicine's top priorities. It has long been known that genetics plays a major role in the development ... -
Investigating the Relationship Between Zetaproteobacteria and Cyanobacteria and its Implications for the Geological Record
(East Carolina University, 2022-07-14)Banded Iron Formations (BIFs) are geological relics of the ancient oceans that were partially formed by microorganisms. This includes oxygenic phototrophs and iron-oxidizing bacteria (FeOB) whose relative contributions are ... -
Investigating the Relationship Between Zetaproteobacteria and Cyanobacteria and its Implications for the Geological Record
(East Carolina University, 2022-07-14)Banded Iron Formations (BIFs) are geological relics of the ancient oceans that were partially formed by microorganisms. This includes oxygenic phototrophs and iron-oxidizing bacteria (FeOB) whose relative contributions are ... -
Investigating the role microRNAs play in the root-knot nematode Meloidogyne incognita’s viability, reproduction, and parasitism in cotton
(East Carolina University, 2023-04-25)Functions of four microRNAs (miRNAs), min-miR1, min-miR71, min-miR100a, and min-miR-124, were investigated in the parasitic nematode Meloidogyne incognita’s (M. incognita’s) overall behavior and mortality. M. incognita is ... -
Investigating the Role of CG8093 in Drosophila Female Germline Stem Cells
(East Carolina University, 2023-05-03)Cell division and differentiation are imperative for the maintenance of living organisms. Germ cells, which serve as the progenitor cells necessary to create oocytes and sperm, are maintained in many organisms by the ... -
Investigating the Role of Conserved Cysteine Residues in Arabidopsis thaliana Diacylglycerol Acyltransferase 1
(East Carolina University, 2021-07-28)Triacylglycerols (TAGs) are biomolecules found in all organisms comprised of three fatty acid chains esterified to a glycerol backbone. In humans, TAGs are important energy storage reserves whose misregulation are associated ... -
Investigating the role of CRL5, an ubiquitin ligase, in ovarian follicle development.
(East Carolina University, 2016-07-20)During oogenesis, follicle cells surround maturing oocytes, which produce factors necessary for proper oocyte growth and development. Correct encapsulation of the oocyte by follicle cells is therefore essential for ... -
Investigating the Role of CtBP in Colorectal Cancer
(2015-04-29)Recent studies in breast cancer tissue have demonstrated that C-terminal binding protein (CtBP) over-expression induces stem cell-like features and genome instability; whereas CtBP depletion or caloric restriction reverses ... -
Investigating the Role of Ecdysone Receptor in Germline to Somatic Cell Communication
(East Carolina University, 2023-12-04)Oogenesis requires complex coordination between both somatic and germ cell populations, relying on systemic signals such as hormones for proper oocyte production and formation. Drosophila melanogaster is an excellent model ... -
Investigating the Role of Poxvirus Virulence Genes A35 and O1L in the Virus Life Cycle
(East Carolina University, 2019-07-22)Poxviruses, some of the largest viruses in existence, have a great impact on the human and animal world due to their ability to infect a broad assortment of organisms and cause significant disease. Today, poxvirus infections ... -
Investigating the role of soil legacy effects and community engagement in the management of Lespedeza cuneata, an invasive legume
(East Carolina University, 2020-11-23)Invasive plant species present a growing threat to biodiversity. Many invasive plants are able to recruit microbial symbionts in their novel range and establish plant-soil feedbacks that influence growth and fitness. These ... -
Investigating the role of TER94 in Drosophila melanogaster germ cells
(East Carolina University, 2021-05-28)Mutations in Valosin-Containing Protein (VCP) can lead to onset of Amyotrophic Lateral Sclerosis, a fatal neurodegenerative disease; however, the intracellular functions of VCP in cells remain unclear. To study the ...