Browsing by Title
Now showing items 5443-5462 of 10630
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Investigating the role of transcription factor, Trl, during germline development in the Drosophila ovary
(East Carolina University, 2019-07-22)Oogenesis is the process by which an egg develops from undifferentiated cells in the ovary. The Drosophila melanogaster ovary is an assembly line for egg production, making it a great system to investigate initial oocyte ... -
Investigating the roles of E-T coupling and social environment in the stimulus-dependent expression of parathyroid hormone 2.
(East Carolina University, 2021-05-28)In larval zebrafish, parathyroid hormone 2 (pth2) codes for a peptide hormone that is expressed exclusively in cells near the ventral part of the posterior tuberculum, an area of the forebrain involved in sensori-motor ... -
Investigating the Safety Challenges of Unmanned Aerial Vehicles (UAVs) in the Construction Environment
(East Carolina University, 2021-12-01)The technologies associated with Unmanned Aerial vehicles (UAVs) have revolutionized the construction industry, simultaneously demanding a comprehensive understanding of the underlying safety implications in order to reduce ... -
Investigating the Seed Bank of a Wetland Plant Community in a Long-Term Mowing and Fertilization Experiment
(East Carolina University, 2023-05-15)The seed bank of a plant community—the store of viable, dormant seeds below the soil surface—holds a legacy of its past composition and may have potential for restoration following habitat degradation. An ongoing 20-year ... -
INVESTIGATING THE STAR SCHEMA BENCHMARK AS A REPLACEMENT FOR THE TPC-H DECISION SUPPORT SYSTEM
(East Carolina University, 2016-12-13)Decision Support System (DSS) are at the core of business intelligence systems. Implementation costs for enterprise level Database Management System (DBMS) and DSS average $10,461 for installation costs. This does not ... -
Investigating the Structural and Functional Roles of Conserved Cysteine Residues in Arabidopsis thaliana Fatty-Acid Desaturase 2
(East Carolina University, 2022-12-06)Plant-generated unsaturated fatty acids (UFAs) and polyunsaturated fatty acids (PUFAs) are vital to a plant's growth and survival through maintenance of plasma membrane fluidity and integrity, in addition to the various ... -
Investigating the Use of Virtual Reality Headsets for Postural Control Assessment: An Instrument Validation Study
(JMIR Publications, 2020-10-11)Accurately measuring postural sway is an important part of balance assessment and rehabilitation. Although force plates give accurate measurements, their costs and space requirements make their use impractical in many ... -
Investigation Into Intermolecular Interactions of Gd3N@C80(OH)n Using Fluorescence Spectroscopy
(2014)The aim of this experiment was to investigate the intermolecular interactions of the endohedral metallofulerene complex in water and various metal cation solutions. These interactions were observed using a methodology ... -
Investigation Into The Scope, Limitations, And Mechanistic Aspects Of A Regioselective Acylation Of Cycloplatinated Complexes
(East Carolina University, 2015)In the reaction of N-isopropyl-N-phenyl-2,2'-bipyridin-6-amine with potassium tetrachloroplatinate, the selective C-H bond activation was complicated by the low selectivity of sp² C-H bond activation in acetonitrile and ... -
An Investigation of Auditory and Visual Temporal Processing in Children with Reading Disorders
(East Carolina University, 2009)Several lines of research have revealed a relationship between reading disorders (RD) and auditory temporal processing deficits. That is, subtle, yet rapid changes within an acoustic message are more difficult for individuals ... -
Investigation of conserved cysteines on 6 fatty acid desaturase function in Arabidopsis thaliana
(East Carolina University, 2021-05-28)Plants are an incredibly diverse group of organisms with over 300,000 species inhabiting different environments worldwide. Recent advances in biotechnology have driven investigations into the biochemical properties of plant ... -
Investigation of Curli-Specific Proteins CsgD and CsgA Reveals a Potential Target for Neurodegenerative Therapeutics and Provides Structural Insights into the Bacterial Amyloid CsgA
(East Carolina University, 2022-12-06)A growing body of evidence implicates curli-containing biofilms in the onset of neurodegenerative pathologies like Alzheimer's and Parkinson's diseases. Curli-containing biofilms are composed primarily of two bacterial ... -
Investigation of Molecular Mechanism of Transthyretin Oligomerization Associated with ATTR Amyloidosis
(East Carolina University, 2022-04-27)Transthyretin amyloidosis (ATTR) has classically been diagnosed predominantly post-observation of amyloid fibril deposition on soft tissues within the body, however, recent studies have shown that oligomers which arise ... -
Investigation of NADPH-Dependent Thioredoxin Reductase-C (NTRC) In Chloroplast Lipid Metabolism
(East Carolina University, 2022-07-01)Redox reactions are ubiquitous within plant metabolism and critical for the sustainment of photosynthesis within thylakoid membranes. Specialized glycerolipids that make up these membranes in turn require redox reactions ... -
Investigation of NADPH-Dependent Thioredoxin Reductase-C (NTRC) In Chloroplast Lipid Metabolism
(East Carolina University, 2022-07-01)Redox reactions are ubiquitous within plant metabolism and critical for the sustainment of photosynthesis within thylakoid membranes. Specialized glycerolipids that make up these membranes in turn require redox reactions ... -
Investigation of Neurodegenerative Disease-related Cofilin-Actin Rod Dynamics Using a Novel Optogenetic Approach
(East Carolina University, 2023-12-15)The presence of actin-cofilin rods in neurons is a common feature of a multitude of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntingtin’s disease (Bamburg, et al 2010). These ... -
Investigation of Nonhydrolyzable ATP Analogues and Cofilin-Derived Peptides for Inhibition of Cofilin-Actin Rod Formation
(East Carolina University, 2021-08-02)Actin-Cofilin rods are an important marker of neurodegenerative disease and are commonly observed in the neurons of patients with Alzheimer's disease. The goal of this research is to investigate peptide and small-molecules ...