Browsing by Title
Now showing items 5451-5470 of 10629
-
Investigation Into Intermolecular Interactions of Gd3N@C80(OH)n Using Fluorescence Spectroscopy
(2014)The aim of this experiment was to investigate the intermolecular interactions of the endohedral metallofulerene complex in water and various metal cation solutions. These interactions were observed using a methodology ... -
Investigation Into The Scope, Limitations, And Mechanistic Aspects Of A Regioselective Acylation Of Cycloplatinated Complexes
(East Carolina University, 2015)In the reaction of N-isopropyl-N-phenyl-2,2'-bipyridin-6-amine with potassium tetrachloroplatinate, the selective C-H bond activation was complicated by the low selectivity of sp² C-H bond activation in acetonitrile and ... -
An Investigation of Auditory and Visual Temporal Processing in Children with Reading Disorders
(East Carolina University, 2009)Several lines of research have revealed a relationship between reading disorders (RD) and auditory temporal processing deficits. That is, subtle, yet rapid changes within an acoustic message are more difficult for individuals ... -
Investigation of conserved cysteines on 6 fatty acid desaturase function in Arabidopsis thaliana
(East Carolina University, 2021-05-28)Plants are an incredibly diverse group of organisms with over 300,000 species inhabiting different environments worldwide. Recent advances in biotechnology have driven investigations into the biochemical properties of plant ... -
Investigation of Curli-Specific Proteins CsgD and CsgA Reveals a Potential Target for Neurodegenerative Therapeutics and Provides Structural Insights into the Bacterial Amyloid CsgA
(East Carolina University, 2022-12-06)A growing body of evidence implicates curli-containing biofilms in the onset of neurodegenerative pathologies like Alzheimer's and Parkinson's diseases. Curli-containing biofilms are composed primarily of two bacterial ... -
Investigation of Molecular Mechanism of Transthyretin Oligomerization Associated with ATTR Amyloidosis
(East Carolina University, 2022-04-27)Transthyretin amyloidosis (ATTR) has classically been diagnosed predominantly post-observation of amyloid fibril deposition on soft tissues within the body, however, recent studies have shown that oligomers which arise ... -
Investigation of NADPH-Dependent Thioredoxin Reductase-C (NTRC) In Chloroplast Lipid Metabolism
(East Carolina University, 2022-07-01)Redox reactions are ubiquitous within plant metabolism and critical for the sustainment of photosynthesis within thylakoid membranes. Specialized glycerolipids that make up these membranes in turn require redox reactions ... -
Investigation of NADPH-Dependent Thioredoxin Reductase-C (NTRC) In Chloroplast Lipid Metabolism
(East Carolina University, 2022-07-01)Redox reactions are ubiquitous within plant metabolism and critical for the sustainment of photosynthesis within thylakoid membranes. Specialized glycerolipids that make up these membranes in turn require redox reactions ... -
Investigation of Neurodegenerative Disease-related Cofilin-Actin Rod Dynamics Using a Novel Optogenetic Approach
(East Carolina University, 2023-12-15)The presence of actin-cofilin rods in neurons is a common feature of a multitude of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntingtin’s disease (Bamburg, et al 2010). These ... -
Investigation of Nonhydrolyzable ATP Analogues and Cofilin-Derived Peptides for Inhibition of Cofilin-Actin Rod Formation
(East Carolina University, 2021-08-02)Actin-Cofilin rods are an important marker of neurodegenerative disease and are commonly observed in the neurons of patients with Alzheimer's disease. The goal of this research is to investigate peptide and small-molecules ... -
Investigation of Platinum-Catalyzed Acylation of 2-Aryloxypyridines via C-H Activation and Functionalization
(East Carolina University, 2022-07-12)Transition metal catalyzed C-H activation and functionalization reactions allow synthetic chemists to break the normally unreactive carbon-hydrogen bond and create a new and useful carbon-oxygen, carbon-nitrogen, carbon-halogen, ... -
Investigation of Platinum-Catalyzed Acylation of 2-Aryloxypyridines via C-H Activation and Functionalization
(East Carolina University, 2022-07-12)Transition metal catalyzed C-H activation and functionalization reactions allow synthetic chemists to break the normally unreactive carbon-hydrogen bond and create a new and useful carbon-oxygen, carbon-nitrogen, carbon-halogen, ... -
Investigation of possible driving forces on counter-intuitive thermal collapse of intrinsically disordered proteins
(East Carolina University, 2016-08-18)Intrinsically disordered proteins are an emerging class of proteins that contain no secondary or tertiary structure. Through bioinformatics studies it has been predicted that a third of the human proteome consists of ... -
Investigation of Safety Culture among Young Workers
(East Carolina University, 2019-04-30)According to the Occupational Safety and Health Administration (OSHA), young workers whose ages range from 14 to 24 and are interested in finding different jobs during the summer or during the school year are considered ... -
Investigation of the Anatomical and Physiological Changes Following the Use of a Pedicled Buccal Fat Pad Graft During Primary Palatoplasty
(East Carolina University, 2019-07-19)Children with cleft palate typically undergo primary surgery between 6-12 months of age to close the cleft in the palate and create proper muscle function for elevation and retraction of the velum for speech. About one ... -
AN INVESTIGATION OF THE TAPHONOMIC EFFECTS OF ANIMAL SCAVENGING
(East Carolina University, 2014)Numerous environmental and human-induced variables that affect decomposition can cloud accurate estimations of the postmortem interval (PMI). For instance, scavenging animals can remove soft tissue and disarticulate and ...