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Now showing items 9712-9731 of 10629
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THE ROLE OF N6-METHYLADENOSINE IN HYPOXIA AND CELLULAR TRANSFORMATION
(East Carolina University, 2017-11-29)Cancer is a prevalent disease that affects millions of people each year across the globe. In an effort to find therapies to the many types of cancers, regulation of protein expression through transcription and translation ... -
The Role of Oatp74D, an Ecdysone Importer, in the Drosophila ovary.
(East Carolina University, 2022-05-04)Oogenesis is the progression of germ cells through mitotic expansion, differentiation into an oocyte, and successful completion of meiosis. Steroid hormones play critical roles in this process in diverse organisms. In ... -
THE ROLE OF PLACE ATTACHMENT AND SENSE OF COMMUNITY IN TAILGATING
(East Carolina University, 2017-05-03)Tailgating is a specialized form of tourism that surrounds most major sporting events. These major sporting events have been studied countlessly to try to understand the behavior of the consumers that attend them, but none ... -
The Role of Pre-Replication Complex Proteins in Drosophila Ovarian Stem Cell Maintenance and Proliferation
(East Carolina University, 2017-05-05)Cancer stem cells (CSCs) may hold the key to advances in cancer research. Like adult tissue-specific stem cells, CSCs are able to self-renew and last a lifetime. These shared characteristics can thus be used to help learn ... -
The Role of Prenatal Hormone Exposure on Associative Learning in a Rat Model of Autism Spectrum Disorder
(East Carolina University, 2017-05-04)Approximately 1 in 68 children are diagnosed with an autism spectrum disorder (ASD), and lifetime costs in the U.S. per child are estimated at $2.3 million. While the precise causes for abnormal brain development in ASD ... -
The Role of Resources and Message Exposure on Health-Related Outcomes
(East Carolina University, 2016-05-03)The current study involved analysis of the relationships between frequency of health message exposure, perceived resource availability, health-related self-efficacy, health-related anxiety, negative rumination, and positive ... -
THE ROLE OF RETINOIC ACID IN DIRECTING INITIATION OF SPERMATOGENESIS IN THE MOUSE
(East Carolina University, 2015-10-23)The basic tenets of gametogenesis are conserved among metazoans. After lineage commitment, germ cells proliferate, complete meiosis, and then differentiate into gametes capable of fertilization. In the mouse, spermatogenesis ... -
THE ROLE OF THE ALVEOLAR MACROPHAGE IN CARBON NANOTUBE ELICITED MURINE MODEL OF PULMONARY GRANULOMATOUS INFLAMMATION
(East Carolina University, 2018-11-29)Pulmonary sarcoidosis is a debilitating inflammatory condition characterized by the presence of granulomatous lesions throughout the lung. Granulomas are a physiological response to inhaled antigens or particulate matter ... -
THE ROLE OF THE LATERAL LINE IN EARLY LARVAL ZEBRAFISH AND CONTRIBUTION TO MULTISENSORY BEHAVIORS
(East Carolina University, 2023-07-21)The lateral line is a hair cell-based sensory system that is important for multisensory behaviors like schooling, rheotaxis, and predator/prey detection in aquatic vertebrates. This dissertation work uses the first genetic ... -
The Role of the Melanocortin-1 Receptor Gene in Müllerian Mimic Ranitomeya imitator
(East Carolina University, 2019-05-02)The Peruvian poison dart frog Ranitomeya imitator has undergone a Müllerian mimetic radiation, which means that this species has evolved color patterns that mimic three other poison dart frogs in different geographic regions ... -
The Role of the Notch-3 Receptor in Stemness, EMT, and Tumorigenesis in Colorectal Cancer
(East Carolina University, 2016-05-05)As the second leading cause of cancer death worldwide, colorectal cancer (CRC) poses a significant threat to both men and women alike. Although a small percentage of CRC cases are inherited, the majority of cases arise ...