Browsing by Author "Azam, Mohammad A."
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Arginase Promotes Neointima Formation in Rat Injured Carotid Arteries
Peyton, Kelly J.; Ensenat, Diana; Azam, Mohammad A.; Keswani, Amit N.; Kannan, Sankaranarayanan; Liu, Xiao-Ming; Wang, Hong; Tulis, David A.; Durante, William (East Carolina University, 2009-04)Objective—Arginase stimulates the proliferation of cultured vascular smooth muscle cells (VSMCs); however, the influence of arginase on VSMC growth in vivo is not known. This study investigated the impact of arginase on ... -
Bilirubin inhibits neointima formation and vascular smooth muscle cell proliferation and migration
Peyton, Kelly J.; Shebib, Ahmad R.; Azam, Mohammad A.; Liu, Xiao-ming; Tulis, David A.; Durante, William (2012-03-22)Bilirubin is a heme metabolite generated by the concerted action of the enzymes heme oxygenase and biliverdin reductase. Although long considered a toxic byproduct of heme catabolism, recent preclinical, and clinical studies ...