Browsing by Author "Banzon, Patrick D."
-
HOW CHARGED RESIDUES INFLUENCE THE THERMAL STABILITY OF COLLAGEN: A STUDY WITH NATURAL AND NON-NATURAL AMINO ACIDS
Banzon, Patrick D. (East Carolina University, 2020-09-16)Triple-helical collagens are key structural proteins in mammals. Their ubiquity and diverse functions drive our interest into understanding their behavior at a fundamental level. This thesis describes a reductionist approach ... -
STABILIZATION OF THE COLLAGEN TRIPLE HELIX WITH A RUTHENIUM(II) ANCHOR
Banzon, Patrick D. (East Carolina University, 2017-05-04)Two collagen analogues based on a (Pro-Hyp-Gly)7 core were given metal-binding ability by linking histidine to either the N- or C- termini using a six-carbon spacer. Circular dichroism studies confirmed that the isomers, ...