Browsing by Author "Baucom, Matthew"
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Installation of Metal-Binding Functionality at Lysine Residues via Azide-Alkyne "Click Chemistry"
Baucom, Matthew (2015-04-29)A novel non-natural amino acid designed to bind divalent metal ions, dubbed Lys(PYRIT), was prepared in a “click reaction” by treating Fmoc-Lys(N3)-OH with 2-ethynylpyridine and Cu(I). It was incorporated into a 12-residue ...