Browsing by Author "Biomedical Science"
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Combating bacterial biofilms: Functional characterization of the Vibrio fischeri biofilm regulatory protein SypE
Abhulimen, Ehime Noah (East Carolina University, 2023-12-15)Antibiotic resistance represents a notable and increasing threat to healthcare and its economics. Biofilms are directly associated with bacterial tolerance to antibiotics. These biofilms are tightly regulated communities ... -
DEFINING THE ABILITY OF SNAT NANOTHERAPEUTIC TO INHIBIT SARS-COV-2 INFECTION AND ALTER THE HOST MICRONOME TO INDUCE AN ANTIVIRAL CELLULAR ENVIRONMENT
Bauer, Anais (East Carolina University, 2023-12-07)MicroRNAs (miRNAs) are regulatory elements that canonically bind to target mRNAs, reducing translation and protein output. They are non-coding strands of RNA, roughly 18-25 nucleotides long, and are found in plants, animals, ... -
Determining the role of BRCA1 in skeletal muscle regeneration
Williamson, Nick (East Carolina University, 2022-07-15)Skeletal muscle is necessary for movement, breathing, and performance of daily activities. Acute injuries can occur to skeletal muscle, and there are several conditions and diseases that result in impairment of muscle ... -
Identification of galectin-1 as a marker for claudin-low breast cancer and implications for tumor progression
Balestrieri, Kassondra (East Carolina University, 2024-01-04)Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Patients with TNBC have a high rate of metastasis and mortality due to the lack of targeted therapies and resistance to chemotherapy. This ... -
Kinin B1 Receptor Mediates Bidirectional Interaction between Neuroinflammation and Oxidative Stress
Theobald, Drew (East Carolina University, 2023-05-02)Hypertension is the leading risk factor for cardiovascular disease and affects nearly half the adults in the United States. It is well established that hypertension is a low-grade inflammatory condition and is associated ...