Browsing by Author "Chitwood, W. Randolph"
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Allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model
Hopson, Steven B.; Lust, Robert M.; Sun, You Su; Zeri, Richard S.; Morrison, Ron F.; Otaki, Masaki; Chitwood, W. Randolph (East Carolina University, 1995-07)The ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (XO)- inhibiting properties. Human myocardium how- ever, has exhibited low levels of XO ... -
Comparison of a New bioprosthetic Mitral Valve to Other Commercially Available Devices Under Controlled Conditions in a Porcine Mode
Chitwood, W. Randolph; Wang, Dee Dee; Caranasos, Thomas G.; O'Neill, Brian P.; Stack, Richard S.; O'Neill, William W. (2021) -
Discharge β-Blocker Use and Race after Coronary Artery Bypass Grafting
O'Neal, Wesley T.; Efird, Jimmy T.; Davies, Stephen W.; O'Neal, Jason B.; Griffin, William F.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2014-04)Introduction: The use of discharge β-blockers after cardiac surgery is associated with a long-term mortality benefit. β-Blockers have been suggested to be less effective in black cardiovascular patients compared with whites. ... -
The economic value of rapid deployment aortic valve replacement via full sternotomy
Moore, Matt; Barnhart, Glenn R.; Chitwood, W. Randolph; Rizzo, John A.; Gunnarsson, Candace; Palli, Swetha R.; Grossi, Eugene A. (2017-04-04)Aim: To compare the economic value of EDWARDS INTUITY EliteTM (EIE) valve system for rapid-deployment aortic valve replacement (RDAVR) in a full sternotomy (FS) approach (EIE-FS-RDAVR) versus FS-AVR using conventional ... -
The effect of race and chronic obstructive pulmonary disease on long-term survival after coronary artery bypass grafting
Efird, Jimmy T.; O'Neal, Wesley T.; Anderson, Curtis A.; O'Neal, Jason B.; Kindell, Linda C.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2013-04)Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: ... -
The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting
Efird, Jimmy T.; O'Neal, Wesley T.; Anderson, Curtis A.; O'Neal, Jason B.; Kindell, Linda C.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2013-04)Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: ... -
Increased Coronary Artery Disease Severity in Black Women Undergoing Coronary Bypass Surgery
Efird, Jimmy T.; O'Neal, Wesley T.; Griffin, William F.; Anderson, Ethan; Davies, Stephen W.; Landrine, Hope; O'Neal, Jason B.; Shiue, Kristin Y.; Kindell, Linda C.; Ferguson, Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2015)Race and sex disparities are believed to play an important role in heart disease. The purpose of this study was to examine the association between race, sex, and number of diseased vessels at the time of coronary artery ... -
Increased Long-Term Mortality among Black CABG Patients Receiving Preoperative Inotropic Agents
Efird, Jimmy T.; Griffin, William F.; Sarpong, Daniel F.; Davies, Stephen W.; Vann, Iulia; Koutlas, Nathaniel T.; Anderson, Ethan; Crane, Patricia B.; Landrine, Hope; Kindell, Linda C.; Iqbal, Zahra J.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2015-07)The aim of this study was to examine racial differences in long-term mortality after coronary artery bypass grafting (CABG), stratified by preoperative use of inotropic agents. Black and white patients who required ... -
Increased Long-Term Mortality among Black CABG Patients Receiving Preoperative Inotropic Agents
Efird, Jimmy T.; Griffin, William F.; Sarpong, Daniel F.; Davies, Stephen W.; Vann, Lulia; Koutlas, Nathaniel T.; Anderson, Ethan; Crane, Patricia B.; Landrine, Hope; Kindell, Linda; Iqbal, Zahra J.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2015-07)The aim of this study was to examine racial differences in long-term mortality after coronary artery bypass grafting (CABG), stratified by preoperative use of inotropic agents. Black and white patients who required ... -
Monoamine Oxidase is a Major Determinant of Redox Balance in Human Atrial Myocardium and is Associated With Postoperative Atrial Fibrillation
Anderson, Ethan; Efird, Jimmy T.; Davies, Stephen W.; O'Neal, Wesley T.; Darden, Timothy M.; Thayne, Kathleen A.; Katunga, Lalage Adalaide; Kindell, Linda C.; Ferguson, T. Bruce; Anderson, Curtis A.; Chitwood, W. Randolph; Koutlas, Theodore C.; Williams, J. Mark; Rodriguez, Evelio; Kypson, Alan P. (2014-02)BACKGROUND: Onset of postoperative atrial fibrillation (POAF) is a common and costly complication of heart surgery despite major improvements in surgical technique and quality of patient care. The etiology of POAF, and ... -
Racial Differences in Survival among Hemodialysis Patients after Coronary Artery Bypass Grafting
Efird, Jimmy T.; O'Neal, Wesley T.; Bolin, Paul Jr.; Davies, Stephen W.; O'Neal, Jason B.; Anderson, Curtis A.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2013-09)The aim of this study was to examine racial differences in long-term survival among hemodialysis patients after coronary artery bypass grafting (CABG). To our knowledge this has not been previously addressed in the literature. ... -
Racial differences in survival among hemodialysis patients after coronary artery bypass grafting
Efird, Jimmy T.; O’Neal, Wesley T.; Bolin, Paul Jr.; Davies, Stephen W.; O’Neal, Jason B.; Anderson, Curtis A.; Ferguson, T. Bruce; Chitwood, W. Randolph; Kypson, Alan P. (2013-09-06)The aim of this study was to examine racial differences in long-term survival among hemodialysis patients after coronary artery bypass grafting (CABG). To our knowledge this has not been previously addressed in the literature. ... -
Risk-adjusted survival after coronary artery bypass grafting: Implications for quality improvement
Efird, Jimmy T.; O’Neal, Wesley T.; Davies, Stephen W.; O’Neal, Jason B.; Kindell, Linda C.; Anderson, Curtis A.; Chitwood, W. Randolph; Ferguson, T. Bruce; Kypson, Alan P. (2014-07-21)Mortality represents an important outcome measure following coronary artery bypass grafting. Shorter survival times may reflect poor surgical quality and an increased number of costly postoperative complications. Quality ... -
Risk-Adjusted Survival after Coronary Artery Bypass Grafting: Implications for Quality Improvement
Efird, Jimmy T.; O'Neal, Wesley T.; Davies, Stephen W.; O'Neal, Jason B.; Kindell, Linda C.; Anderson, Curtis A.; Chitwood, W. Randolph; Ferguson, T. Bruce; Kypson, Alan P. (2014-07)Mortality represents an important outcome measure following coronary artery bypass grafting. Shorter survival times may reflect poor surgical quality and an increased number of costly postoperative complications. Quality ... -
Robotic Surgical Training in an Academic Institution
Chitwood, W. Randolph; Nifong, L. Wiley; Chapman, William H. H.; Felger, Jason E.; Bailey, B. Marcus; Ballint, Tara; Mendleson, Kim G.; Kim, Victor B.; Young, James A.; Albrecht, Robert A. (East Carolina University, 2001-10)Objective To detail robotic procedure development and clinical applications for mitral valve, biliary, and gastric reflux operations, and to implement a multispecialty robotic surgery training curriculum for both ... -
TRANSFORM (Multicenter Experience With Rapid Deployment Edwards INTUITY Valve System for Aortic Valve Replacement) US clinical trial: Performance of a rapid deployment aortic valve
Barnhart, Glenn R.; Accola, Kevin D.; Grossi, Eugene A.; Woo, Y. Joseph; Mumtaz, Mubashir A.; Sabik, Joseph F.; Slachman, Frank N.; Patel, Himanshu J.; Borger, Michael A.; Garrett, H. Edward Jr.; Rodriguez, Evelio; McCarthy, Patrick M.; Ryan, William H.; Duhay, Francis G.; Mack, Michael J.; Chitwood, W. Randolph; TRANSFORM Trial Investigators (2017-02)Background: The TRANSFORM (Multicenter Experience With Rapid Deployment Edwards INTUITY Valve System for Aortic Valve Replacement) trial (NCT01700439) evaluated the performance of the INTUITY rapid deployment aortic valve ...