Browsing by Author "Gogarten, Stephanie M."
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Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial
Keene, Keith L.; Chen, Wei-Min; Chen, Fang; Williams, Stephen R.; Elkhatib, Stacey D.; Hsu, Fang-Chi; Mychaleckyj, Josyf C.; Doheny, Kimberly F.; Pugh, Elizabeth W.; Ling, Hua; Laurie, Cathy C.; Gogarten, Stephanie M.; Madden, Ebony B.; Worrall, Bradford B.; Sale, Michele M. (2014-08)Background: B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke. We performed a genome-wide association study ... -
Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of with Ischemic Stroke
Williams, Stephen R.; Yang, Qiong; Chen, Fang; Liu, Xuan; Keene, Keith L.; Jacques, Paul; Chen, Wei-Min; Weinstein, Galit; Hsu, Fang-Chi; Beiser, Alexa; Wang, Liewei; Bookman, Ebony; Doheny, Kimberly F.; Wolf, Philip A.; Zilka, Michelle; Selhub, Jacob; Nelson, Sarah; Gogarten, Stephanie M.; Worrall, Bradford B.; Seshadri, Sudha; Sale, Michèle M. (2014-03)Circulating homocysteine levels (tHcy), a product of the folate one carbon metabolism pathway (FOCM) through the demethylation of methionine, are heritable and are associated with an increased risk of common diseases such ...