Browsing by Author "Hudson, Nathan E"
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EVALUATING THE USE OF TURBIDIMETRY FOR STUDYING FIBRIN STRUCTURAL PROPERTIES
Belcher, Heather A (East Carolina University, 2023-04-21)A fibrin fiber mesh forms the structural backbone of blood clots. Many pathological conditions result in fibrin gels with altered structural properties, so there is interest in developing rapid and accurate ways to ... -
Studying Collagen with PyrATS: Pyrene-Appended Trimeric Systems
Keever, Jared Matthew (East Carolina University, 2019-07-30)Collagens are a family of triple-helical structural proteins that are ubiquitous in vertebrates. Improper folding of collagen can lead to disorders such as osteogenesis imperfecta, or "brittle bone disease." There is ... -
The Role of N-Linked Glycosylation on Human Fibrinogen: A Structure-Function Analysis Utilizing Affinity and High-Performance Liquid Chromatography
Daub, Caroline Elizabeth (East Carolina University, 2023-05-05)Fibrinogen (Fgn) is a soluble, 3-chain homodimeric glycoprotein found in blood plasma that is involved in forming blood clots. It is the precursor to fibrin, an insoluble protein that forms the structural scaffold of blood ...