Browsing by Author "Huo, Shouquan"
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EXPLORATION INTO THE SCOPE AND MECHANISM OF THE PLATINUM-CATALYZED ACYLATION OF 2-(ARYLOXY)PYRIDINES
Guthrie, Jacob D (East Carolina University, 2019-07-11)Transition metal catalysts have played a key role in direct C-H bond functionalization. However, one main drawback of these reactions is that oxidants and additives are often required to regenerate the active catalyst, ... -
Investigation Into The Scope, Limitations, And Mechanistic Aspects Of A Regioselective Acylation Of Cycloplatinated Complexes
Carroll, Jeffrey Samuel (East Carolina University, 2015)In the reaction of N-isopropyl-N-phenyl-2,2'-bipyridin-6-amine with potassium tetrachloroplatinate, the selective C-H bond activation was complicated by the low selectivity of sp² C-H bond activation in acetonitrile and ... -
Investigation of Platinum-Catalyzed Acylation of 2-Aryloxypyridines via C-H Activation and Functionalization
Barham, Alex Meacham (East Carolina University, 2022-07-12)Transition metal catalyzed C-H activation and functionalization reactions allow synthetic chemists to break the normally unreactive carbon-hydrogen bond and create a new and useful carbon-oxygen, carbon-nitrogen, carbon-halogen, ... -
Platinum Catalyzed Synthesis of Alpha-Ketoester via C-H Functionalization
Javed, Erman (East Carolina University, 2019-12-16)Alpha-ketoesters have proven to be useful in a variety of fields. They have found wide spread applications in pharmaceuticals, photochemistry, and biology. Additionally, they are of great interest in synthetic chemistry ... -
Platinum-Catalyzed Acylation of 2-(aryloxy)pyridines Via Direct Carbon-Hydrogen Activation
McAteer, Donald (East Carolina University, 2017-05-24)Carbonyl groups are ubiquitous in pharmaceuticals, biomolecules, and natural products. The traditional means of acylation to introduce carbonyls, such as the Friedel-Crafts acylation, can be limited in scope. More recent ... -
Regiospecific acylation of cycloplatinated complexes. Scope, limitations, and mechanism.
Woolard, Hannah (East Carolina University, 2016-05-02)Recently we have discovered a regioselective acylation of cyclometalated platinum complexes in which the cyclometalated platinum complex was selectively acylated by reacting with acetic anhydride in acetic acid. It was ... -
Solvent-Controlled Switch of Selectivity between sp[superscript]2 and s[superscript]p3 C-H Bond Activation by Platinum (II)
Garner, Alexander William (East Carolina University, 2010)Cyclometalation reactions have been studied intensely for the past few decades, especially those containing palladium. The factors that control the process of the C-H bond activation, however, are not yet completely ... -
SYNTHESIS AND PHOTOPHYSICAL CHARACTERIZATION OF TRIDENTATE C^N*N PLATINUM (II) COMPLEXES and, INVESTIGATION OF SELECTIVITY IN C-H BOND ACTIVATION BY PLATINUM
Ravindranathan, Deepak (East Carolina University, 2012)The synthesis, structure, and photophysical properties of a series of novel, highly luminescent tridentate platinum complexes with general coordination geometry of (C^N*N)-PtL are reported, where "C^N" denotes a coordination ... -
Synthesis and Reactions of Novel Heteroarylzirconocene Reagents
Harris, Caleb F. (East Carolina University, 2012)The cross-coupling of metallated heteroaromatic species with aryl and heteroaryl halides is a powerful and highly desirable transformation in both the synthesis of pharmaceutical compounds as well as materials development. ... -
Synthesis, structure, photophysics, and biological activity of platinum (II) complexes
Vezzu, Dileep Atchyuth Kumar (East Carolina University, 2013)The synthesis, structure, and photophysical properties of luminescent platinum (II) complexes with different coordination patterns, (C^C*N^N), (N^C*N), (N^N*C) and (N^N^C) are reported, where "C^N or N^N" denotes a bidentate ... -
THE SYNTHESIS, STRUCTURE AND PHOTOPHYSICAL PROPERTIES OF PHOSPHORESCENT CYCLOMETALATED N^N^C-COORDINATED PLATINUM COMPLEXES
Mroz, Robert (East Carolina University, 2016-07-25)Phosphorescent materials based on cyclometalated platinum complexes have attracted a great deal of attention because of their potential in chemical, biological and optoelectronic applications, specifically as emitters in ...