Browsing by Author "Kwak, Hyo-Bum"
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Effects of exercise on obesity-induced mitochondrial dysfunction in skeletal muscle
Heo, Jun-Won; No, Mi-Hyun; Park, Dong-Ho; Kang, Ju-Hee; Seo, Dae Yun; Han, Jin; Neufer, P. Darrell; Kwak, Hyo-Bum (2017-11)Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all as- sociated with mitochondrial dysfunction in skeletal muscle. ... -
Overexpression of Long-Chain Acyl-CoA Synthetase 5 Increases Fatty Acid Oxidation and Free Radical Formation While Attenuating Insulin Signaling in Primary Human Skeletal Myotubes
Kwak, Hyo-Bum; Woodlief, Tracey L.; Green, Thomas D.; Cox, Julie H.; Hickner, Robert C.; Neufer, P. Darrell; Cortright, Ronald N. (2019-03-31)In rodent skeletal muscle, acyl-coenzyme A (CoA) synthetase 5 (ACSL-5) is suggested to localize to the mitochondria but its precise function in human skeletal muscle is unknown. The purpose of these studies was to define ...