Browsing by Author "Manzoli, Lucia"
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Lamin B1 Accumulation’s Effects on Autosomal Dominant Leukodystrophy (ADLD): Induction of Reactivity in the Astrocytes
Ratti, Stefano; Rusciano, Isabella; Mongiorgi, Sara; Neri, Irene; Alessandra Cappellini, Alessandra; Cortelli, Pietro; Suh, Pann-Ghill; McCubrey, James A.; Manzoli, Lucia; Cocco, Lucio; Ramazzotti, Giulia (2021-09-28) -
A novel DAG-dependent mechanism links PKCa and Cyclin B1 regulating cell cycle progression
Poli, Alessandro; Ramazzotti, Giulia; Matteucci, Alessandro; Manzoli, Lucia; Lonetti, Annalisa; Suh, Pann-Ghill; McCubrey, James A.; Cocco, Lucio (2014-11)Through the years, different studies showed the involvement of Protein Kinase C (PKC) in cell cycle control, in particular during G1/S transition. Little is known about their role at G2/M checkpoint. In this study, using ... -
Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes
Follo, Matilde Y.; Pellagatt, Andrea; Armstrong, Richard N.; Ratti, Stefano; Mongiorgi, Sara; Fanti, Sara De; Bochicchio, Maria Teresa; Russo, Domenico; Gobbi, Marco; Miglino, Maurizio; Parisi, Sarah; Martinelli, Giovanni; Cavo, Michele; Luiselli, Donata; McCubrey, James A.; Suh, Pann-Ghill; Manzoli, Lucia; Boultwood, Jacqueline; Finelli, Carlo; Cocco, Lucio (2019-02-20)Specific myeloid-related and inositide-specific gene mutations can be linked to myelodysplastic syndromes (MDS) pathogenesis and therapy. Here, 44 higher-risk MDS patients were treated with azacitidine and lenalidomide and ...