Browsing by Author "Martin, Daniel W."
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The cation diffusion facilitator family protein EmfA confers resistance to manganese toxicity in Brucella abortus 2308 and is an essential virulence determinant in mice
Johnsrude, Matthew; Pitzer, Joshua E.; Martin, Daniel W.; Roop, R. Martin (2019-04-01)Brucella abortus is a Gram-negative bacterium that causes abortion and infertility in food animals and a chronic debilitating febrile disease in humans known as brucellosis. As with all pathogenic bacteria, the Brucella ... -
Invasion and Intracellular Survival of Burkholderia cepacia
Martin, Daniel W.; Mohr, Christian D. (East Carolina University, 2000-01)Burkholderia cepacia has emerged as an important pulmonary pathogen in immunocompromised patients and in patients with cystic fibrosis (CF). Little is known about the virulence factors and pathogenesis of B. cepacia, ... -
The Manganese Transporter MntH Is a Critical Virulence Determinant for Brucella abortus 2308 in Experimentally Infected Mice
Anderson, Eric; Paulley, James T.; Gaines, Jennifer M.; Valderas, Michelle W.; Martin, Daniel W.; Menscher, Evan A.; Brown, Timothy D.; Burns, Colin Sanderson; Roop II, R. Martin (East Carolina University, 2009-08)The gene designated BAB1_1460 in the Brucella abortus 2308 genome sequence is predicted to encode the manganese transporter MntH. Phenotypic analysis of an isogenic mntH mutant indicates that MntH is the sole high-affinity ...