Browsing by Author "Thomson, David M."
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Does AMP-Activated Protein Kinase Negatively Mediate Aged Fast-Twitch Skeletal Muscle Mass?
Gordon, Scott Edward; Lake, Jordan A.; Westerkamp, Christopher M.; Thomson, David M. (East Carolina University, 2008-10)The activity of 5'-adenosine monophosphate–activated protein kinase, a negative regulator of cell size, is up-regulated with age in resting and overloaded fast-twitch skeletal muscle but not slowtwitch muscle. Here, we ... -
Impaired overload-induced muscle growth is associated with diminished translational signalling in aged rat fast-twitch skeletal muscle
Thomson, David M.; Gordon, Scott Edward (East Carolina University, 2006-07-01)Impaired overload-induced protein synthesis and growth in aged fast-twitch skeletal muscle may result from diminished responsiveness of signalling intermediates controlling protein translation. Yet, potential age-related ...