Browsing by Author "Vahdati, Ali"
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A Patient-Specific Multiscale Model of Mechanical Ventilation of COVID-19-afflicted Lungs
Middleton, Shea Taran (East Carolina University, 2022-07-24)Coronavirus disease-2019 (COVID-19) is a respiratory disease that caused a worldwide pandemic and, in some cases, manifests as an acute respiratory distress syndrome. Severe cases of COVID-19 are often treated with mechanical ... -
A Patient-Specific Multiscale Model of Mechanical Ventilation of COVID-19-afflicted Lungs
Middleton, Shea Taran (East Carolina University, 2022-07-24)Coronavirus disease-2019 (COVID-19) is a respiratory disease that caused a worldwide pandemic and, in some cases, manifests as an acute respiratory distress syndrome. Severe cases of COVID-19 are often treated with mechanical ... -
Collagen matricryptin promotes cardiac function by mediating scar formation
Grilo, Gabriel A.; Cakir, Sirin N.; Shaver, Patti R.; Iyer, Rugmani P.; Whitehead, Kaitlin; McClung, Joseph M.; Vahdati, Ali; de Castro Brás, Lisandra E. (2023-05-15)Aims A peptide mimetic of a collagen-derived matricryptin (p1159) was shown to reduce left ventricular (LV) dilation and fibrosis after 7 days delivery in a mouse model of myocardial infarction (MI). This suggested p1159 ... -
Influence of Perivascular Adipose Tissue on Central Arterial Mechanics and Hemodynamics: A Parametric Fluid Structure Interaction Analysis
Huda, Fatma Tahsin (East Carolina University, 8/5/2020)This study aims to evaluate the biomechanical influence of perivascular adipose tissue (PVAT) on arterial wall mechanics and hemodynamics, which are key regulators in cardiovascular disease progression. Fluid-structure ... -
Physics-Based Computational Modeling of Mechanics and Perfusion in COVID-19 Infected Lungs
Dimbath, Elizabeth (East Carolina University, 2022-07-15)SARS-CoV-2 is the newest virus to lead to severe respiratory illness and reach global pandemic status in its spread. Histopathological studies as well as global lung dynamics of the disease state of COVID-19 resemble acute ... -
Physics-Based Computational Modeling of Mechanics and Perfusion in COVID-19 Infected Lungs
Dimbath, Elizabeth (East Carolina University, 2022-07-15)SARS-CoV-2 is the newest virus to lead to severe respiratory illness and reach global pandemic status in its spread. Histopathological studies as well as global lung dynamics of the disease state of COVID-19 resemble acute ... -
Towards a Multi-Scale Computer Modeling Workflow for Simulation of Pulmonary Ventilation in Advanced COVID-19
Middleton, Shea; Dimbath, Elizabeth; Pant, Anup; George, Stephanie M.; Vahdati, Ali; Peach, M. Sean; Yang, Kaida; Ju, Andrew W.; Maddipati, Veeranna (2022)